EARLY CYTOKINE PREDICTORS OF ACUTE REJECTION OF KIDNEY TRANSPLANT
- Authors: Fedorenko T.V.1,2, Kolesnikova N.V.1, Pashkova I.A.2
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Affiliations:
- “Kuban state medical University” of the Ministry of health care of the Russian Federation
- Regional coordination center of organ donation of the Regional clinical hospital № 1
- Issue: Vol 22, No 2-1 (2019)
- Pages: 590-591
- Section: ORIGINAL ARTICLES
- URL: https://ogarev-online.ru/1028-7221/article/view/120311
- DOI: https://doi.org/10.31857/S102872210006984-7
- ID: 120311
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Abstract
The study of the protective role of blood cytokines evaluated by multiplex analysis before kidney transplantation in recipients with chronic kidney disease showed that the predictors of acute kidney transplant rejection in recipients can be considered high plasma levels of IL-17A, IL-1RA, IL-33, CCL2, as well as BDNF and ccl1 defi ciency. The early signs of a favorable post-transplant period are complete absence or extremely low levels of IL-1β, IL-6, IL-17A, decreased levels of LIF, IL-33, CXCL12), as well as high levels of CXCL8, CXCL10, IFNγ and CCL5.
Keywords
About the authors
T. V. Fedorenko
“Kuban state medical University” of the Ministry of health care of the Russian Federation;Regional coordination center of organ donation of the Regional clinical hospital № 1
Author for correspondence.
Email: fake@neicon.ru
post-graduate student of the Department of Clinical immunology, allergology and laboratory diagnostics;
laboratory biologist,
Krasnodar
Russian FederationN. V. Kolesnikova
“Kuban state medical University” of the Ministry of health care of the Russian Federation
Email: nvk24071954@mail.ru
professor of the Department of Clinical immunology, allergology and laboratory diagnostics,
Krasnodar
Russian FederationI. A. Pashkova
Regional coordination center of organ donation of the Regional clinical hospital № 1
Email: fake@neicon.ru
professor of the Department of Clinical immunology, allergology and laboratory diagnostics,
Krasnodar
Russian FederationReferences
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