STUDY OF ANTIBODIES TO β2-GLYKOPROTEIN-I AND DOMAIN I IN WOMEN WITH RECURRENT PREGNANCY LOSS
- 作者: Menzhinskaya I.V.1, Van’ko L.V.1
-
隶属关系:
- National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V. I. Kulakov of the Ministry of Healthcare of Russian Federation
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 403-405
- 栏目: ORIGINAL ARTICLES
- URL: https://ogarev-online.ru/1028-7221/article/view/120164
- DOI: https://doi.org/10.31857/S102872210006911-7
- ID: 120164
如何引用文章
全文:
详细
Antibodies to β2-GP-I are an independent risk factor for recurrent pregnancy loss (RPL).A good agreement between the results of ELISA and chemiluminescent immunoassay was shown in the determination of medium and high anti-β2-GP-I antibody concentrations. Antibodies to domain I were often found in the patients seropositive for anti-β2-GP-I antibodies. Detection of antibodies to domain I has important clinical significance for the stratification of patients by risk of thrombosis and obstetric complications.
作者简介
I. Menzhinskaya
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V. I. Kulakov of the Ministry of Healthcare of Russian Federation
编辑信件的主要联系方式.
Email: i_menzinskaya@oparina4.ru
PhD in Medical sciences, Senior Researcher of the Laboratory of Clinical Immunology,
Moscow
俄罗斯联邦L. Van’ko
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V. I. Kulakov of the Ministry of Healthcare of Russian Federation
Email: fake@neicon.ru
д. м. н., профессор, ведущий научный сотрудник лаборатории клинической иммунологии,
Москва
俄罗斯联邦参考
- Willis R., Pierangeli S. S. Anti-β2-glycoprotein I antibodies. Ann. N. Y. Acad.Sci. 2013, 1285, 44–58.
- Менжинская И. В., Кащенцева М. М., Ионанидзе Т. Б., Ванько Л. В., Сухих Г. Т. Спектр антифосфолипидных антител у женщин с привычным невынашиванием беременности и их диагностическое значение. Иммунология. 2016, 37(1), 4–9.
- Saccone G., Berghella V., Maruotti G. M., Ghi T., Rizzo G., Simonazzi G., Rizzo N., Facchinetti F., Dall’Asta A., Visentin S., Sarno L., XodovS., Bernabini D., Monari F., Roman A., Chigoziem Eke A., Hoxha A., Ruff atti A., Schuit E., Martinelli P. Antiphospholipid antibody profi le based obstetric outcomes of primary antiphospholipid syndrome: the pregnants study. Am. J. Obstet. Gynecol. 2017, 216, 525.e1–525.e12.
- De Craemer A. S., Musial J., Devreese K. M. Role of anti-domain 1-β2 glycoprotein I antibodies in the diagnosis and risk stratifi cation of antiphospholipid syndrome. J. Thromb. Haemost. 2016, 14(9), 1779–1787.
补充文件
