INFLUENCE OF OPSONINS OF FRESH AND INACTIVATED UNDER 56 °C BLOOD SERUM ON ZYMOSAN-INDUCED PRODUCTION OF REACTIVE OXYGEN SPECIES BY RAT LEUCOCYTES
- Authors: Shilov J.I.1,2, Godovalov A.P.2, Shilov D.J.3, Shilov S.J.1,2, Eliáš D.4
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Affiliations:
- “Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences” – a branch of the PFRC UB RAS
- Acad. E. A. Wagner Perm State Medical University
- LLC MC “Family Doctor”
- Charles University
- Issue: Vol 22, No 2-2 (2019)
- Pages: 981-983
- Section: ORIGINAL ARTICLES
- URL: https://ogarev-online.ru/1028-7221/article/view/120152
- DOI: https://doi.org/10.31857/S102872210006498-2
- ID: 120152
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About the authors
Ju. I. Shilov
“Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences” – a branch of the PFRC UB RAS;Acad. E. A. Wagner Perm State Medical University
Author for correspondence.
Email: jshilov@mail.ru
PhD, MD, Associate Professor, Leading Researcher,
Perm
Russian FederationA. P. Godovalov
Acad. E. A. Wagner Perm State Medical University
PhD, MD, Leading Researcher of Central Scientifi c Research Laboratory and Associate Professor of the Department of Microbiology and Virology,
Perm
Russian FederationD. Ju. Shilov
LLC MC “Family Doctor”
PhD, MD, Allergist-Immunologist, Leading Specialist,
Moscow
Russian FederationS. Ju. Shilov
“Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences” – a branch of the PFRC UB RAS;Acad. E. A. Wagner Perm State Medical University
PhD, MD, Junior Researcher,
Moscow
Russian FederationD. Eliáš
Charles University
medical student, Faculty of Medicine in Hradec Kralove,
Hradec Kralove
Russian FederationReferences
- Makni-Maalej K., Chiandotto M., Hurtado-Nedelec M., Bedouhene S., Gougerot-Pocidalo M. A., Dang P. M., ElBenna J. Zymosan induces NADPH oxidase activation in human neutrophils by inducing the phosphorylation of p47phox and the activation of Rac2: involvement of protein tyrosine kinases, PI3Kinase, PKC, ERK1/2 and p38MAPkinase. Biochem Pharmacol. 2013, 85(1), 92–100.
- Morris M. R., Dewitt S., Laffafian I., Hallett M. B. Phagocytosis by inflammatory phagocytes: experimental strategies for stimulation and quantification. Methods Mol. Biol. 2003, 225, 35–46.
- Mankovich A. R., Lee C. Y., Heinrich V. Differential effects of serum heat treatment on chemotaxis and phagocytosis by human neutrophils. PLoS One 2013, 8(1), e54735. doi: 10.1371/journal.pone.0054735.
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