THE ANALYSIS OF PERIPHERAL BLOOD CYTOKINES IN WOMEN WITH RECURRENT SPONTANEOUS ABORTION
- 作者: Kroshkina N.V.1, Kust A.V.1, Kozelkova E.V.1
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隶属关系:
- Federal State Budget Establishment «Ivanovo Research Institute of Maternity and Childhood named after V. N. Gorodkova» of the Ministry of Health of Russia
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 344-346
- 栏目: ORIGINAL ARTICLES
- URL: https://ogarev-online.ru/1028-7221/article/view/119935
- DOI: https://doi.org/10.31857/S102872210006622-9
- ID: 119935
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详细
The level of IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70, IL-13, IL-17A, IL-18, IL-21, IL-22, IL-23, IL-27, IFNγ, TNFα, GM-CSF in the peripheral blood of women with recurrent spontaneous abortion and uncomplicated pregnancy was investigated at 5–12 weeks of gestation. It was established, that the serum level of IL-1β, IL-22, IL-23 and IL-27 in women with habitual abortion increased, and the tendency to the elevation of serum level of IL-10 и IL-13 was seen.
作者简介
N. Kroshkina
Federal State Budget Establishment «Ivanovo Research Institute of Maternity and Childhood named after V. N. Gorodkova» of the Ministry of Health of Russia
Email: fake@neicon.ru
PhD, researcher of the laboratory of clinical immunology,
Ivanovo
俄罗斯联邦A. Kust
Federal State Budget Establishment «Ivanovo Research Institute of Maternity and Childhood named after V. N. Gorodkova» of the Ministry of Health of Russia
编辑信件的主要联系方式.
Email: niimid.immune@mail.ru
postgraduate Student of the laboratory of clinical immunology,
Ivanovo
俄罗斯联邦E. Kozelkova
Federal State Budget Establishment «Ivanovo Research Institute of Maternity and Childhood named after V. N. Gorodkova» of the Ministry of Health of Russia
Email: fake@neicon.ru
postgraduate Student of the Department of Obstetrics and Gynecology, Neonatology, Anesthesiology and Reanimatology,
Ivanovo
俄罗斯联邦参考
- Zhao X., Jiang Y., Wang L., Li Z., Li Q., Feng X. Advances in understading the immune imbalance between T-lymphocyte subsets and NK cells in recurrent spontaneous abortion. Geburtshilfe Fraunheilkd. 2018, 78(7), 677–683.
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- Caprioli F., Sarra M., Caruso R., Stolfi C., Fina D., Sica G., MacDonald T. T., Pallone F., Monteleone G. Autocrine regulation of IL-21 production in human T lymphocytes. J Immunol. 2008, 180(3), 1800–1807.
- Zotos D., Coquet J. M., Zhang Y., Light A., D’Costa K., Kallies A., Corcoran L. M., Godfrey D. I., Toellner K. M., Smyth M. J., Nutt S. L., Tarlinton D. M. IL-21 regulates germinal center B cell diff erentiation and proliferation through a B cell-intrinsic mechanism. J Exp Med. 2010, 207(2), 365–378.
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