INFLUENCE OF GLUTAMYL-TRYPTOPHAN ON CYTOKINE SECRETION, WOUND HEALING, AND ANTIOXIDANT SYSTEM IN VITRO AND IN VIVO
- Authors: Kudriavtceva T.A.1, Starikova E.A.2, Voronkina I.V.3, Smirnov V.S.1
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Affiliations:
- ZAO MPSPS CYTOMED
- Institute of Experimental Medicine
- Institute of Cytology of the Russian Academy of Sciences (RAS)
- Issue: Vol 22, No 2-2 (2019)
- Pages: 834-836
- Section: ORIGINAL ARTICLES
- URL: https://ogarev-online.ru/1028-7221/article/view/119694
- DOI: https://doi.org/10.31857/S102872210006681-4
- ID: 119694
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Abstract
Dipeptide glutamyl-tryptophan influences on metabolic processes in different cells, stimulates the functional activity of immune cells, restores disorders in the antioxidant system, improves tissue regeneration, accelerates wound healing, activates the functions of connective tissue cells, endotheliocytes, macrophages and leukocytes in the outbreak damage.
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About the authors
T. A. Kudriavtceva
ZAO MPSPS CYTOMED
Author for correspondence.
Email: tkudriavtceva@cytomed.ru
PhD, Chief Scientific Officer Department of Science,
St Petersburg
Russian FederationE. A. Starikova
Institute of Experimental Medicine
PhD Leading Reseacher Department of Immunology,
St Petersburg
Russian FederationI. V. Voronkina
Institute of Cytology of the Russian Academy of Sciences (RAS)
PhD Leading Reseacher Department of Cell Cultures,
St Petersburg
Russian FederationV. S. Smirnov
ZAO MPSPS CYTOMED
MD, Professor, Heard of Department of Science,
St Petersburg
Russian FederationReferences
- Смирнов В. С., Петленко С. В. Комплексный препарат «Цитовир-3». В кн.: Грипп и острые респираторные вирусные инфекции (характериcтика, патогенез, профилактика и лечение), изд. 3-е перераб. и доп. – СПб: Гиппократ 2019. 128–163.
- Shevtsov M. A., Smagina L. V., Kudriavtceva T. A., Vo ronkina I. V. Glu-Trp-ONa or its acylated analogue (R-GluTrp-ONa) administration enhances the wound healing in the model of chronic skin wounds in rabbits. Drug Design, Development and Therapy 2015:9, 1717–1727.
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