IMMUNOTROPIC INFLUENCE OF RHODOCOCCUS-BIOSURFACTANT IN VIVO
- Authors: Kochina O.A.1, Kuyukina M.S.1,2, Ivshina I.B.1
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Affiliations:
- Institute of ecology and genetics of microorganisms
- Perm State University
- Issue: Vol 20, No 3 (2017)
- Pages: 396-398
- Section: Articles
- URL: https://ogarev-online.ru/1028-7221/article/view/119577
- ID: 119577
Cite item
Abstract
Microbial biosurfactant complex Rhodococcus ruber IEGM 231 has immunoregulatory properties. It was established that the glycolipid complex and its dominant fraction of monoacyltrehalose exerted a depressing effect on innate and acquired immunity of laboratory mice with intraperitoneal and intramuscular injection.
About the authors
O. A. Kochina
Institute of ecology and genetics of microorganisms
Author for correspondence.
Russian Federation
M. S. Kuyukina
Institute of ecology and genetics of microorganisms; Perm State UniversityRussian Federation
I. B. Ivshina
Institute of ecology and genetics of microorganismsRussian Federation
References
- Paulino B. N., Pessoa M. G., Mano M. C. R. Current status in biotechnological production and applications of glycolipid biosurfactants. Appl Microbiol Biotechnol. 2016, (100 (24)), 10265-10293.
- Shao Z. Trehalolipids. In: Biosurfactants from genes to applications. Soberon-Chavez G (ed), Springer-Verlag, Berlin 2011, 216.
- Куюкина М. С., Ившина И. Б., Гейн С. В., Баева Т. А., Черешнев В. А. In vitro иммуномодулирующая активность биосурфактантного гли-колипидного комплекса из Rhodococcus ruber. Бюллетень экспериментальной биологии и медицины. 2007, 144 (9), 301-305.
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