DEVELOPMENT OF MODELS OF HUMAN MALIGNANT TUMORS FOR CELLULAR IMMUNOTHERAPY
- Authors: Zlatnik E.Y.1, Maksimov A.Y.1, Goncharova A.S.1, Karnaukhov N.S.1
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Affiliations:
- Federal Budget Institution Rostov Research Institute of Oncology
- Issue: Vol 22, No 2-2 (2019)
- Pages: 775-777
- Section: ORIGINAL ARTICLES
- URL: https://ogarev-online.ru/1028-7221/article/view/119553
- DOI: https://doi.org/10.31857/S102872210006702-7
- ID: 119553
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Abstract
Development of ectopic and orthotopic models of human malignant tumors in nude mice with consequent morphologic and immunologic studies was carried out. Morphologic compliancy of tumors having grown in mice to the initial ones was shown. Divergent immunologic changes were found in animals with ectopic and orthotopic tumors.
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About the authors
E. Y. Zlatnik
Federal Budget Institution Rostov Research Institute of Oncology
Author for correspondence.
Email: elena-zlatnik@mail.ru
MD, Prof., Chief Researcher, Laboratory of Immunophenotyping of Tumors,
Rostov-on-Don
Russian FederationA. Yu. Maksimov
Federal Budget Institution Rostov Research Institute of Oncology
MD., Professor, Deputy General Director for Advanced Scientific Developments,
Rostov-on-Don
Russian FederationA. S. Goncharova
Federal Budget Institution Rostov Research Institute of Oncology
Ph D., Head of Experimental Laboratory Center,
Rostov-on-Don
Russian FederationN. S. Karnaukhov
Federal Budget Institution Rostov Research Institute of Oncology
Ph D., Head of Department of Pathological Anatomy,
Rostov-on-Don
Russian FederationReferences
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