Alkylation of Ethyl 2-Aryl-1-hydroxy-4-methyl-1H-imidazole-5-carboxylates with Benzyl Halides

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

Alkylation of ethyl 2-aryl-1-hydroxy-4-methyl-1H-imidazole-5-carboxylates with substituted benzyl hal-ides led to the selective formation of O-alkoxy derivatives. Products of N-alkylation(1-alkylimidazole 3-oxides) could be obtained by condensation reaction from acyclic starting compounds. If a 2-hydroxy-phenyl moiety was present in position 2 of imidazole ring, then monoalkylation proceeded selectively at hydroxy group of the nitrogen atom of heterocycle.

Авторлар туралы

P. Nikitina

D.I. Mendeleev University of Chemical Technology of Russia

Email: polinandrevna@yandex.ru
Moscow, Russia

I. Os’kina

N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Science

Novosibirsk, Russia

E. Nikolaenkova

N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Science

Novosibirsk, Russia

E. Kulikova

D.I. Mendeleev University of Chemical Technology of Russia

Moscow, Russia

V. Miroshnikov

D.I. Mendeleev University of Chemical Technology of Russia

Moscow, Russia

V. Perevalov

D.I. Mendeleev University of Chemical Technology of Russia

Moscow, Russia

A. Tikhonov

N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Science

Novosibirsk, Russia

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