LUJO HEMORRHAGIC FEVER
- Authors: Sizikova T.E.1, Lebedev V.N.1, Syromyatnikova S.I.1, Borisevich S.V.1
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Affiliations:
- 48th Central Scientific Research Institute
- Issue: Vol 62, No 4 (2017)
- Pages: 149-153
- Section: REVIEWS
- URL: https://ogarev-online.ru/0507-4088/article/view/117919
- DOI: https://doi.org/10.18821/0507-4088-2017-62-4-149-153
- ID: 117919
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Abstract
Lujo hemorrhagic fever (LHF) is a viral disease accompanied with fever, headache, vomiting, diarrhea, arthralgia, myalgia and numerous signs of hemorrhagic syndrome. LHF causes a clinical syndrome remarkably similar to Lassa hemorrhagic fever. The first case of LHF occurred in Johannesburg, South Africa, in 2008. There was a secondary transmission from the index patient to four healthcare workers. Four of the five patients died. The etiologic agent of LHF is Lujo virus (LUJV) belonging to Arenavirus genus of the Arenaviridae Family. Virus Lujo is the second pathogenic arenavirus, after Lassa virus, to be recognized in Africa during the last 40 years. Data about epidemiology, clinical characteristics and diagnostics of LHF, properties of Lujo virus (according to phylogenetic analysis), and recommended precautions for preventing secondary transmission are considered in this paper.
About the authors
T. E. Sizikova
48th Central Scientific Research Institute
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
V. N. Lebedev
48th Central Scientific Research Institute
Email: noemail@neicon.ru
Russian Federation
S. I. Syromyatnikova
48th Central Scientific Research Institute
Email: noemail@neicon.ru
Russian Federation
S. V. Borisevich
48th Central Scientific Research Institute
Email: 48cnii@mil.ru
Russian Federation
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