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Electrophysical and biological properties in vitro of lithium doped hydroxyapatite
- Authors: Goldberg M.A.1, Gafurov M.R.2, Lounev I.V.2, Fomin A.S.1, Smirnov S.V.1, Obolkina T.O.1, Antonova O.S.1, Akhmedova S.A.3, Kirsanova V.A.3, Sviridova I.K.3, Sergeeva N.S.3, Leonov A.V.4, Barinov S.M.4, Komlev V.S.1
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Affiliations:
- Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences
- Institute of Physics, Kazan Federal University
- P.A. Hertsen Moscow Oncology Research Institute, National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
- Lomonosov Moscow State University
- Issue: Vol 89, No 10 (2025)
- Pages: 1605-1615
- Section: Physics of magnetic phenomena: fundamental and applied research using magnetic resonance methods
- URL: https://ogarev-online.ru/0367-6765/article/view/375825
- DOI: https://doi.org/10.7868/S3034646025100126
- ID: 375825
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Abstract
The impact of varying lithium concentrations introduced into hydroxyapatite has been extensively documented, spanning a wide range of concentrations from 1 to 20 mol.%. It has been demonstrated that an increase in the content of Li+ ions is associated with enhanced growth of relative dielectric permittivity. Concurrently, the introduction of lithium does not elicit acute cytotoxicity and is conducive to the proliferation of MG-63 cells in vitro, as observed over a seven-day period.
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About the authors
M. A. Goldberg
Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences
Email: mgoldberg@imet.ac.ru
Moscow, Russia
M. R. Gafurov
Institute of Physics, Kazan Federal University
Email: mgoldberg@imet.ac.ru
Kazan, Russia
I. V. Lounev
Institute of Physics, Kazan Federal University
Email: mgoldberg@imet.ac.ru
Kazan, Russia
A. S. Fomin
Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences
Email: mgoldberg@imet.ac.ru
Moscow, Russia
S. V. Smirnov
Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences
Email: mgoldberg@imet.ac.ru
Moscow, Russia
T. O. Obolkina
Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences
Email: mgoldberg@imet.ac.ru
Moscow, Russia
O. S. Antonova
Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences
Email: mgoldberg@imet.ac.ru
Moscow, Russia
S. A. Akhmedova
P.A. Hertsen Moscow Oncology Research Institute, National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
Email: mgoldberg@imet.ac.ru
Moscow, Russia
V. A. Kirsanova
P.A. Hertsen Moscow Oncology Research Institute, National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
Email: mgoldberg@imet.ac.ru
Moscow, Russia
I. K. Sviridova
P.A. Hertsen Moscow Oncology Research Institute, National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
Email: mgoldberg@imet.ac.ru
Moscow, Russia
N. S. Sergeeva
P.A. Hertsen Moscow Oncology Research Institute, National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
Email: mgoldberg@imet.ac.ru
Moscow, Russia
A. V. Leonov
Lomonosov Moscow State University
Email: mgoldberg@imet.ac.ru
Chemical Department
Moscow, RussiaS. M. Barinov
Email: mgoldberg@imet.ac.ru
V. S. Komlev
Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences
Author for correspondence.
Email: mgoldberg@imet.ac.ru
Moscow, Russia
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