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Study of flash effects at the proton accelerator of INR RAS
- Authors: Akulinichev S.V.1,2
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Affiliations:
- Institute for Nuclear Research of the Russian Academy of Sciences
- Petrovsky National Research Center of Surgery
- Issue: Vol 89, No 8 (2025)
- Pages: 1194-1200
- Section: Fundamental problems and applications of physics of atomic nucleus
- URL: https://ogarev-online.ru/0367-6765/article/view/356109
- DOI: https://doi.org/10.7868/S3034646025080033
- ID: 356109
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Abstract
A brief overview of the results and methods for conducting radiobiological experiments to study the patterns of flash effect at the linear proton accelerator of INR RAS is presented. An increase in apoptosis of tumor cells compared to normal cells was found when the dose rate increased to extreme values.
Keywords
About the authors
S. V. Akulinichev
Institute for Nuclear Research of the Russian Academy of Sciences; Petrovsky National Research Center of Surgery
Email: akulinic@inr.ru
Moscow, Russia; Moscow, Russia
References
- Favaudon V., Caplier L., Monceau V. et al. // Sci. Transl. Med. 2014. V. 6. No. 245. Art. No. 245ra93.
- Atkinson J., Bezak E., Le H., Kempson I. // Phys. Eng. Sci. Med. 2023. V. 46. P. 529.
- Mohamad O., Sishc B.J., Saha J. et al. // Cancers. 2017. V. 9. No. 6. P. 66.
- Sørensen B.S., Sitarz M.K., Ankjærgaard C. et al. // Radiother. Oncol. 2022. V. 175. P. 178.
- Weiss H. // Radiat. Res. V. 1972. V. 50. P. 441.
- Hu A., Qiu R., Li W.B. et al. // Int. J. Rad. Biol. 2022. V. 99. No. 4. P. 620.
- Colangelo N.W., Azzam E.I. // Radiat. Res. 2020. V. 193. P. 1.
- Вайнсон А.А., Соловьева Е.В. // Онкол. журн.: луч. диагн., луч. терапия. 2022. Т. 5. № 4. С. 9.
- Акулиничев С.В., Гаврилов Ю.К., Коконцев Д.А., Яковлев И.А. // ПТЭ. 2018. Т. 61. № 6. С. 116.
- Djilkibaev R.M. // Instrum. Exper. Tech. 2021. V. 64. No. 4. P. 503.
- Акулиничев С.В., Гаврилов Ю.К., Джилкибаев Р.М. // ПТЭ. 2023. Т. 3. С. 5.
- Сербин М.Е., Щербак Е.В. // Актуальн. пробл. биол., мед. и экологии. 2004. Т. 1. С. 46.
- Voigt G.L., Swist S.L. Hematology Techniques and Concepts for Veterinary Technicians. WileyBlackwell, 2011. P. 208.
- Akulinichev S.V., Gavrilov Yu.K., Glukhov S.I. et al. // Bull. Russ. Acad. Sci. Phys. 2023. V. 87. No. 8. P. 1224.
- Akulinichev S.V., Glukhov S.I., Kuznetsova E.A. et al. // Intern. J. Radiat. Biol. 2024.
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