Assessment of Glycogen and Lipid Contents in Neutrophil Leukocytes of Peripheral Blood during Prenosological Diagnosis of Flight Personnel

Аннотация

The flight factors in highly maneuverable aircrafts lead to a significant and early progress of maladaptive shifts in pilot’s body as compared with non-flying professions. The aim of this study was to find out whether glycogen and lipid contents in segmented neutrophils of pilot peripheral blood depend on age and total flight hours, and to use findings for prenosological diagnostics of maladaptive shifts in body. The results of cytochemical studies of the content of glycogen and lipids in neutrophils from peripheral blood of pilots during their training flights are given. It has been established that a persistent increase in lipid content in neutrophils with an mean cytochemical coefficient higher than 2.60, along with a decrease in glycogen content in these cells at less than 2.00, indicates a decrease in the energy reserves of phagocytes, and peripheral blood leukocyte cell maladaptation. This condition develops as a response of the pilot’s body to the complex effect of flight factors on highly maneuverable aircraft with a total flight time of more than 1500 h and a pilot age of 36 years or more. The revealed patterns can be used in prenosological diagnostics of flight personnel.