Influence of the course of treatment by injections of ozonized saline on rheological properties of erythrocytes in patients with complex pathology

Abstract

The study was carried out to evaluate rheological properties of erythrocytes by comprehensive methods of piezodynamic aggregometry in a microvolume and gradient ektacytometry in patients with complex pathology before and after every injection of ozonized physiological saline. It has been shown that administration of physiological saline and each session of ozone therapy cause reduction of minimal aggregate strength and spontaneous aggregation rate, microviscosity decreases, and deformability and water permeability of erythrocyte membranes increase. The dynamics of changes in the studied parameters of erythrocytes shows an improvement of the blood rheological properties in the patients not only immediately after the procedure, but and after 2 weeks, 1 and 2 months after the course.