Pregnancies with successful delivery after radical trachelectomy in a patient with cervical cancer

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Abstract

Background: According to statistics, cervical cancer is one of the most common neoplastic diseases affecting women both in the world and in the Russian Federation. At the same time, there has been an increase in the number of patients of reproductive age. In this regard, the issue of organ preservation treatment of cervical cancer and extending the patient’s reproductive potential without compromising oncological efficacy becomes relevant. The method of radical trachelectomy (RT) is appropriate for this condition. RT is already included in international treatment standards, but it requires the accumulation of clinical experience.

Case report: A 25-year-old patient was diagnosed with stage IB1 (T1N0M0) cervical cancer. Considering the early stage of the disease, the young age of the patient, and her desire to preserve her fertility, organ-sparing surgery with combined laparoscopic and vaginal access was chosen as the preferred treatment option. Over the next 10 years, the patient did not experience any relapses or malignancies. She was able to become pregnant three times, once through IVF and twice naturally, with two successful deliveries by cesarean section.

Conclusion: The presented case demonstrates that performing organ-sparing RT in case of cervical cancer provides an opportunity of successful and even multiple childbirth in the future without the progression of malignant neoplastic diseases.

About the authors

Vadim V. Popov

Voronezh Regional Scientific and Clinical Oncology Center

Email: popov_vadim@mail.ru

PhD, Head of the Gynecology Department

Russian Federation, Voronezh

Ivan P. Moshurov

Voronezh Regional Scientific and Clinical Oncology Center; N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia

Email: moshurov@vokod.vrn.ru

Dr. Med. Sci., Chief Physician, Voronezh Regional Scientific and Clinical Oncology Center; Chief Freelance Oncologist at the Department of Health of the Voronezh Region; Head of the Department of Oncology, N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia

Russian Federation, Voronezh; Voronezh

Alexander N. Redkin

N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia

Email: oncology@vsmaburdenko.ru

Dr. Med. Sci., Professor at the Department of Oncology

Russian Federation, Voronezh

Yaroslav V. Popov

N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia

Email: yarik_popov-v_00@bk.ru
ORCID iD: 0009-0001-0379-3849

first year resident at the Oncology Department

Russian Federation, Voronezh

Anastasia A. Popova

N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia

Author for correspondence.
Email: nastya_solo202002@mail.ru
ORCID iD: 0000-0002-3904-9253

first year resident at the Oncology Department

Russian Federation, Voronezh

Oksana V. Porotkova

Voronezh Regional Clinical Hospital No. 1

Email: popova_oxanav@mail.ru

PhD, Hematologist

Russian Federation, Voronezh

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