Clinical value of positron emission tomography combined with computed tomography and computed tomography in the diagnosis of diseases of the maxillary sinus
- Authors: Beteeva M.Y.1, Zaderenko I.A.2, Mkrtchyan K.S.1, Sysolyatin S.P.1,3, Kanin R.V.4
-
Affiliations:
- Peoples Friendship University of Russia named after Patrice Lumumba
- N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
- A.I. Burnazyan Federal Medical Biophysical Center of the Federal Medical and Biological Agency of Russia
- Clinic "Zhemchuzhina Podolia"
- Issue: Vol 36, No 11 (2025)
- Pages: 85-88
- Section: From Practice
- URL: https://ogarev-online.ru/0236-3054/article/view/362948
- DOI: https://doi.org/10.29296/25877305-2025-11-14
- ID: 362948
Cite item
Abstract
Precise methods of radial diagnostics of maxillary sinus diseases are rarely used nowadays due to their limited availability. At the same time, the high importance of computed tomography (CT) and positron emission tomography combined with CT (PET-CT) in the accurate diagnosis of hyperplastic inflammatory and non-inflammatory diseases of the maxillary sinus cannot be ignored.
The article presents 3 clinical cases of inverted maxillary sinus papilloma diagnosed in patients with chronic rhinosinusitis. Diagnosis was performed by CT, CT and PET-CT, CT and MRI. Treatment included centripetal rhinoscopic resection. Median follow-up in the postoperative period was 36.2 (24; 41) months. PET-CT demonstrated high efficiency in diagnostics of neoplasm in a patient with nonspecific signs of inverted papilloma - absence of ossification foci. Further study of the aspects of PET-CT application in the diagnosis of maxillary sinus diseases on larger samples within the framework of randomized trials is required.
About the authors
M. Yu. Beteeva
Peoples Friendship University of Russia named after Patrice Lumumba
Author for correspondence.
Email: beteeva95_95@mail.ru
ORCID iD: 0009-0006-4173-6876
SPIN-code: 7282-1528
Russian Federation, Moscow
I. A. Zaderenko
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: beteeva95_95@mail.ru
ORCID iD: 0000-0003-0183-4827
SPIN-code: 4479-0045
MD
Russian Federation, MoscowK. S. Mkrtchyan
Peoples Friendship University of Russia named after Patrice Lumumba
Email: beteeva95_95@mail.ru
ORCID iD: 0000-0002-6040-0052
SPIN-code: 2330-1239
Russian Federation, Moscow
S. P. Sysolyatin
Peoples Friendship University of Russia named after Patrice Lumumba; A.I. Burnazyan Federal Medical Biophysical Center of the Federal Medical and Biological Agency of Russia
Email: beteeva95_95@mail.ru
ORCID iD: 0000-0002-5794-9087
SPIN-code: 2050-5215
Professor, MD
Russian Federation, Moscow; MoscowR. V. Kanin
Clinic "Zhemchuzhina Podolia"
Email: beteeva95_95@mail.ru
ORCID iD: 0009-0001-4772-3260
Russian Federation, Podolsk
References
- Lou H., Fang J., Li P. et al. Frequency, suppressive capacity, recruitment and induction mechanisms of regulatory T cells in sinonasal squamous cell carcinoma and nasal inverted papilloma. PLoS One. 2015; 10 (5): e0126463. doi: 10.1371/journal.pone.0126463
- Paehler Vor der Holte A., Fangk I., Glombitza S. et al. Impact of human papillomaviruses (HPV) on recurrence rate and malignant progression of sinonasal papillomas. Cancer Med. 2021; 10 (2): 634–41. doi: 10.1002/cam4.3642
- Resteghini C., Castelnuovo P., Nicolai P. et al. The SINTART 1 study. A phase II non-randomised controlled trial of induction chemotherapy, surgery, photon-, proton- and carbon ion-based radiotherapy integration in patients with locally advanced resectable sinonasal tumours. Eur J Cancer. 2023; 187: 185–94. doi: 10.1016/j.ejca.2023.03.033
- Naghdi S., Ansari N.N., Varedi M. et al. Use of low-level laser therapy for patients with chronic rhinosinusitis: a single-blind, sham-controlled clinical trial. Lasers Med Sci. 2022; 38 (1): 5. doi: 10.1007/s10103-022-03684-z
- Takahashi D., Demizu Y., Park S.C. et al. Phase I dose-escalation trial of S-1 combined with carbon-ion radiotherapy for sinonasal squamous cell carcinoma. J Radiat Res. 2020; 61 (5): 733–9. doi: 10.1093/jrr/rraa037
- Yeom S,. Lee D.H., Lim S.C. Clinical outcomes of sinonasal inverted papilloma: a retrospective analysis of 139 cases. J Laryngol Otol. 2023; 137 (10): 1154–7. DOI: 10.1017/ S0022215123000361
- Lee J.J., Roland L.T., Licata J.J. et al. Morphologic, intraoperative, and histologic risk factors for sinonasal inverted papilloma recurrence. Laryngoscope. 2020; 130 (3): 590–6. doi: 10.1002/lary.28078
- Peng R., Thamboo A., Choby G. et al. Outcomes of sinonasal inverted papilloma resection by surgical approach: an updated systematic review and metaanalysis. Int Forum Allergy Rhinol. 2019; 9 (6): 573–81. doi: 10.1002/alr.22305
- Ferrari M., Schreiber A., Mattavelli D. et al. How aggressive should resection of inverted papilloma be? Refinement of surgical planning based on the 25-year experience of a single tertiary center. Int Forum Allergy Rhinol. 2020; 10 (5): 619–28. doi: 10.1002/alr.22541
Supplementary files
