Features of patients with infertility against the background of metabolic syndrome
- Authors: Maslov S.S.1, Chilova R.A.1, Siordia A.A.1, Zholobova M.N.1, Kovalev M.I.1, Gadaeva I.V.1, Kazakov R.E.2, Sokova E.A.1,2
-
Affiliations:
- I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
- Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Health of Russia
- Issue: Vol 36, No 7 (2025)
- Pages: 78-80
- Section: From Practice
- URL: https://ogarev-online.ru/0236-3054/article/view/310709
- DOI: https://doi.org/10.29296/25877305-2025-07-13
- ID: 310709
Cite item
Open Access
Access granted
Subscription Access
Abstract
Metabolic syndrome negatively affects the quality of life of patients, leads to infertility and, therefore, a decrease in the birth rate. Features of patients with infertility against the background of metabolic syndrome are considered.
Full Text
##article.viewOnOriginalSite##About the authors
S. S. Maslov
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Author for correspondence.
Email: rtchilova@gmail.com
ORCID iD: 0009-0007-1215-1059
Russian Federation, Moscow
R. A. Chilova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Email: rtchilova@gmail.com
ORCID iD: 0000-0001-6331-3109
SPIN-code: 4137-4848
Professor, MD
Russian Federation, MoscowA. A. Siordia
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Email: rtchilova@gmail.com
ORCID iD: 0000-0002-8796-6443
SPIN-code: 5610-4780
Candidate of Medical Sciences
Russian Federation, MoscowM. N. Zholobova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Email: rtchilova@gmail.com
ORCID iD: 0000-0003-2842-2910
Professor, MD
Russian Federation, MoscowM. I. Kovalev
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Email: rtchilova@gmail.com
ORCID iD: 0000-0002-0426-587X
SPIN-code: 2539-6420
Professor, MD
Russian Federation, MoscowI. V. Gadaeva
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Email: rtchilova@gmail.com
ORCID iD: 0000-0003-0144-4984
SPIN-code: 9593-1990
Associate Professor, Candidate of Medical Sciences
Russian Federation, MoscowR. E. Kazakov
Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Health of Russia
Email: rtchilova@gmail.com
ORCID iD: 0000-0003-0802-4229
SPIN-code: 8751-5090
Candidate of Medical Sciences
Russian Federation, MoscowE. A. Sokova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Health of Russia
Email: rtchilova@gmail.com
ORCID iD: 0000-0002-6389-2099
SPIN-code: 5550-4650
Candidate of Medical Sciences
Russian Federation, Moscow; MoscowReferences
- Carson S.A., Kallen A.N. Diagnosis and Management of Infertility: A Review. JAMA. 2021; 326 (1): 65–76. doi: 10.1001/jama.2021.4788
- Broughton D.E., Moley K.H. Obesity and female infertility: potential mediators of obesity's impact. Fertil Steril. 2017; 107 (4): 840–7. doi: 10.1016/j.fertnstert.2017.01.017
- Talmor A., Dunphy B. Female obesity and infertility. Best Pract Res Clin Obstet Gynaecol. 2015; 29 (4): 498–506. doi: 10.1016/j.bpobgyn.2014.10.014
- Ennab F. Atiomo W. Obesity and female infertility. Best Pract Res Clin Obstet Gynaecol. 2023; 89: 102336. doi: 10.1016/j.bpobgyn.2023.102336
- Chen C.-I., Hsu M.-I., Lin S.-H. et al. Adiponectin and leptin in overweight/obese and lean women with polycystic ovary syndrome. Gynecol Endocrinol. 2015; 31 (4): 264–8. doi: 10.3109/09513590.2014.984676
- van der Steeg J.W., Steures P., Eijkemans M.J.C. et al. Obesity affects spontaneous pregnancy chances in subfertile, ovulatory women. Hum Reprod. 2008; 23 (2): 324–8. doi: 10.1093/humrep/dem371
- Silvestris E., de Pergola G., Rosania R. et al.Obesity as disruptor of the female fertility. Reprod Biol Endocrinol. 2018; 16 (1): 22. doi: 10.1186/s12958-018-0336-z
- McCartney C.R., Marshall J.C. Clinical Practice. Polycystic Ovary Syndrome. N Engl J Med. 2016; 375 (1): 54–64. doi: 10.1056/NEJMcp1514916
- Gesink Law D.C., Maclehose R.F., Longnecker M.P. Obesity and time to pregnancy. Hum Reprod. 2007; 22 (2): 414–20. doi: 10.1093/humrep/del400
- Pascuali N., Scotti L., Di Pietro M. et al. Ceramide-1-phosphate has protective properties against cyclophosphamide-induced ovarian damage in a mice model of premature ovarian failure. Hum Reprod. 2018; 33 (5): 844–59. doi: 10.1093/humrep/dey045
- Vilmann L.S., Thisted E., Baker J.L. et al. Development of obesity and polycystic ovary syndrome in adolescents. Horm Res Paediatr. 2012; 78 (5-6): 269–78. doi: 10.1159/000345310
- Barrea L., Muscogiuri G., Pugliese G. et al. Metabolically Healthy Obesity (MHO) vs. Metabolically Unhealthy Obesity (MUO) Phenotypes in PCOS: Association with Endocrine-Metabolic Profile, Adherence to the Mediterranean Diet, and Body Composition. Nutrients. 2021; 13 (11): 3925. doi: 10.3390/nu13113925
- Bright K., Dube L., Hayden K.A. et al. Effectiveness of psychological interventions on mental health, quality of life and relationship satisfaction for individuals and/or couples undergoing fertility treatment: a systematic review and meta-analysis protocol. BMJ Open. 2020; 10 (7): e036030. doi: 10.1136/bmjopen-2019-036030
- Хабибулина М.М., Елистратов Д.Г. Психокоррекционая терапия пациенток с «метаболически здоровым» ожирением. Врач. 2024; 35 (4): 36–41 [Khabibulina M., Elistratov D. Psycho-correction therapy of patients with «metabolically healthy» obesity. Vrach. 2024; 35 (4): 36–41 (in Russ.)]. doi: 10.29296/25877305-2024-04-07
Supplementary files
