The use of osteoinductive materials in the treatment of bone pathologies and severe fractures
- Authors: Markov P.A.1, Rozhkova E.A.1, Eremin P.S.1, Marchenkova L.A.1
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Affiliations:
- National Medical Research Center for Rehabilitation and Balneology, Ministry of Health of Russia
- Issue: Vol 35, No 11 (2024)
- Pages: 14-17
- Section: Topical Subject
- URL: https://ogarev-online.ru/0236-3054/article/view/272308
- DOI: https://doi.org/10.29296/25877305-2024-11-02
- ID: 272308
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Abstract
Treatment of bone pathologies and severe fractures is an urgent healthcare problem that requires effective and innovative approaches to ensure complete restoration of bone tissue and improve the quality of life of patients. Traditional methods of bone tissue regeneration, such as transplantation of bone autografts and allografts, have a number of limitations, including a shortage of donor material and the risk of complications. In this regard, it is of interest to use osteoinductive materials that promote accelerated healing and restoration of bone structures.
The article discusses modern osteoinductive materials, their types, mechanisms of action and clinical application. Particular attention is paid to their role in the treatment of complex fractures and bone pathologies, such as osteoporosis and osteomyelitis.
Data from clinical studies have been analyzed demonstrating the high effectiveness of osteoinductive materials in the treatment of complex fractures, osteomyelitis, osteonecrosis and other bone pathologies. Benefits of using these materials include accelerated healing, reduced risk of complications, minimized need for autografts, and improved integration with bone tissue.
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##article.viewOnOriginalSite##About the authors
P. A. Markov
National Medical Research Center for Rehabilitation and Balneology, Ministry of Health of Russia
Email: ereminps@gmail.com
ORCID iD: 0000-0002-4803-4803
Cand. Sci. (Biol.)
Russian Federation, Moscow
E. A. Rozhkova
National Medical Research Center for Rehabilitation and Balneology, Ministry of Health of Russia
Email: ereminps@gmail.com
ORCID iD: 0000-0002-2440-9244
Dr. Sci. (Biol.)
Russian Federation, MoscowP. S. Eremin
National Medical Research Center for Rehabilitation and Balneology, Ministry of Health of Russia
Email: ereminps@gmail.com
ORCID iD: 0000-0001-8832-8470
Dr. Sci. (Med.)
Russian Federation, MoscowL. A. Marchenkova
National Medical Research Center for Rehabilitation and Balneology, Ministry of Health of Russia
Author for correspondence.
Email: ereminps@gmail.com
ORCID iD: 0000-0003-1886-124X
MD
Russian Federation, MoscowReferences
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