Improved Process for Zoledronic Acid Synthesis
- 作者: Kuvaeva Z.I.1, Lopatik D.V.1, Bondareva O.M.1
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隶属关系:
- Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
- 期: 卷 53, 编号 3 (2019)
- 页面: 264-266
- 栏目: Drug Synthesis Methods and Manufacturing Technology
- URL: https://ogarev-online.ru/0091-150X/article/view/245722
- DOI: https://doi.org/10.1007/s11094-019-01989-y
- ID: 245722
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详细
Zoledronic acid is the drug substance of the highly efficient antiresorptive medicine Zometa. An improved synthesis of zoledronic acid via bis-phosphonation of 2-(1H-imidazol-1-yl)acetic acid is reported.
作者简介
Z. Kuvaeva
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Email: aminoacid1@ifoch.bas-net.by
白俄罗斯, Minsk
D. Lopatik
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
编辑信件的主要联系方式.
Email: aminoacid1@ifoch.bas-net.by
白俄罗斯, Minsk
O. Bondareva
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Email: aminoacid1@ifoch.bas-net.by
白俄罗斯, Minsk
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