Enviar artigo por via de e-mail Improved Process for Zoledronic Acid Synthesis
- Autores: Kuvaeva Z.I.1, Lopatik D.V.1, Bondareva O.M.1
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Afiliações:
- Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
- Edição: Volume 53, Nº 3 (2019)
- Páginas: 264-266
- Seção: Drug Synthesis Methods and Manufacturing Technology
- URL: https://ogarev-online.ru/0091-150X/article/view/245722
- DOI: https://doi.org/10.1007/s11094-019-01989-y
- ID: 245722
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Resumo
Zoledronic acid is the drug substance of the highly efficient antiresorptive medicine Zometa. An improved synthesis of zoledronic acid via bis-phosphonation of 2-(1H-imidazol-1-yl)acetic acid is reported.
Sobre autores
Z. Kuvaeva
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Email: aminoacid1@ifoch.bas-net.by
Belarus, Minsk
D. Lopatik
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Autor responsável pela correspondência
Email: aminoacid1@ifoch.bas-net.by
Belarus, Minsk
O. Bondareva
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Email: aminoacid1@ifoch.bas-net.by
Belarus, Minsk
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