Synthesis and Antimicrobial Activity of 3-Phenyl-1-Methylquinolin-2-One Derivatives

O. V. Elenich; R. Z. Lytvyn; O. V. Blinder; O. V. Skripskaya; O. S. Lyavinets; Kh. E. Pitkovych; M. D. Obushak; P. I. Yagodinets

doi:10.1007/s11094-019-01935-y

Synthesis and Antimicrobial Activity of 3-Phenyl-1-Methylquinolin-2-One Derivatives

作者: Elenich O.V.¹, Lytvyn R.Z.², Blinder O.V.³, Skripskaya O.V.¹, Lyavinets O.S.¹, Pitkovych K.E.², Obushak M.D.², Yagodinets P.I.¹
隶属关系:
1. Yuriy Fedkovych Chernivtsi National University
2. Ivan Franko National University of Lviv
3. L. I. Medved Research Center of Preventive Toxicology, Food and Chemical Safety, Department of Medical and Environmental Problems, Ministry of Health
期: 卷 52, 编号 12 (2019)
页面: 969-974
栏目: Article
URL: https://ogarev-online.ru/0091-150X/article/view/245563
DOI: https://doi.org/10.1007/s11094-019-01935-y
ID: 245563

如何引用文章

全文:

开放存取

##reader.subscriptionAccessGranted##
受限制的访问

订阅存取

详细
作者简介
参考
补充文件
统计

详细

A series of quaternary salts were obtained by reacting 3-(4-bromoacetylphenyl)-1-methylquinolin-2(1H)-one with Py, 4-methylpyridine, quinoline, benzo[f]quinoline, and triphenylphosphine. Derivatives of thiazole, imidazo[1,2-a]pyridine, and imidazo[1,2-a]pyrimidine were produced using dinucleophilic reagents. Several of the synthesized compounds possessed high antimicrobial activity, indicating that further research on this series of compounds was promising.