Immobilization of Benzocaine in Polymeric Nanocontainers. Pharmacokinetic Modeling
- 作者: Shkurenko G.Y.1, Lyrshchikov S.Y.1, Gorlov A.A.1, Al’tshuler O.G.1,2, Al’tshuler G.N.1
- 
							隶属关系: 
							- Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
- Kemerovo State University
 
- 期: 卷 52, 编号 5 (2018)
- 页面: 464-466
- 栏目: Drug Synthesis Methods and Manufacturing Technology
- URL: https://ogarev-online.ru/0091-150X/article/view/245249
- DOI: https://doi.org/10.1007/s11094-018-1840-3
- ID: 245249
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详细
The possibility of immobilizing benzocaine in polymeric nanocontainers made of sulfonated cation exchangers, i.e., sulfonated polycalixarene and KU-23 30/100, was studied. The desorption kinetics of neutral and cationic benzocaine from the polymeric nanocontainers provided the desired drug-release pharmacokinetics upon peroral administration.
作者简介
G. Shkurenko
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
														Email: altshulerh@gmail.com
				                					                																			                												                	俄罗斯联邦, 							18 Prosp. Sovetskii, Kemerovo, 650000						
S. Lyrshchikov
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
														Email: altshulerh@gmail.com
				                					                																			                												                	俄罗斯联邦, 							18 Prosp. Sovetskii, Kemerovo, 650000						
A. Gorlov
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
														Email: altshulerh@gmail.com
				                					                																			                												                	俄罗斯联邦, 							18 Prosp. Sovetskii, Kemerovo, 650000						
O. Al’tshuler
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences; Kemerovo State University
							编辑信件的主要联系方式.
							Email: altshulerh@gmail.com
				                					                																			                												                	俄罗斯联邦, 							18 Prosp. Sovetskii, Kemerovo, 650000; 6 Krasnaya St., Kemerovo, 650043						
G. Al’tshuler
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
														Email: altshulerh@gmail.com
				                					                																			                												                	俄罗斯联邦, 							18 Prosp. Sovetskii, Kemerovo, 650000						
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