Development of a Procedure for Identification of Biperiden Hydrochloride with Specificity for Triperiden Hydrochloride

N. E. Kuz’mina; S. V. Moiseev; V. I. Krylov; A. A. Kutin; V. A. Yashkir; V. A. Merkulov

doi:10.1007/s11094-018-1749-x

Development of a Procedure for Identification of Biperiden Hydrochloride with Specificity for Triperiden Hydrochloride

作者: Kuz’mina N.E.¹, Moiseev S.V.¹, Krylov V.I.¹, Kutin A.A.¹, Yashkir V.A.¹, Merkulov V.A.¹
隶属关系:
1. Scientific Center for Expert Evaluation of Medical Products, Ministry of Health of the Russian Federation
期: 卷 51, 编号 12 (2018)
页面: 1106-1110
栏目: Article
URL: https://ogarev-online.ru/0091-150X/article/view/244931
DOI: https://doi.org/10.1007/s11094-018-1749-x
ID: 244931

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Biperiden hydrochloride, (1RS)-1-[(1RS, 2SR, 4RS)-bicyclo[2.2.1]hept-5-en-2-yl]-1-phenyl-3-(piperidin-1-yl)prop an-1-ol hydrochloride, is one of the most efficacious cholinolytics. It is used to treat Parkinson’s disease and various types of muscular spasms and to ameliorate uncoordinated muscular movements that can accompany the use of several tranquilizers [1, 2]. Biperiden appears in the vital and essential drug list that was approved by an order of the RF Government [3].