电邮这篇文章 Kilogram-Scale Pilot Synthesis of Fingolimod
- 作者: Balaev A.N.1, Busel A.A.1, Fedorov V.E.1
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隶属关系:
- Farm-Sintez Co.
- 期: 卷 51, 编号 6 (2017)
- 页面: 476-479
- 栏目: Drug Synthesis Methods and Manufacturing Technology
- URL: https://ogarev-online.ru/0091-150X/article/view/244659
- DOI: https://doi.org/10.1007/s11094-017-1636-x
- ID: 244659
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详细
A kilogram-scale synthesis of fingolimod drug substance was developed using a 30-L pilot setup. The target product was obtained by a four-step procedure in 99.8% purity and 47% overall yield.
作者简介
A. Balaev
Farm-Sintez Co.
Email: chem@folium.ru
俄罗斯联邦, 29/134 Vereiskaya St., Moscow, 121357
A. Busel
Farm-Sintez Co.
Email: chem@folium.ru
俄罗斯联邦, 29/134 Vereiskaya St., Moscow, 121357
V. Fedorov
Farm-Sintez Co.
Email: chem@folium.ru
俄罗斯联邦, 29/134 Vereiskaya St., Moscow, 121357
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