Отправить статью по E-mail Anisotropic Iron-Oxide Nanoparticles for Diagnostic MRI: Synthesis and Contrast Properties
- Авторы: Nikitin A.A.1,2, Khramtsov M.A.1, Savchenko A.G.1, Abakumov M.A.1,3, Mazhuga A.G.2,4
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Учреждения:
- National University of Science and Technology MISIS (Moscow Institute of Steel and Alloys)
- Department of Chemistry, M. V. Lomonosov Moscow State University
- N. I. Pirogov Russian National Research Medical University
- D. I. Mendeleev University of Chemical Technology of Russia
- Выпуск: Том 52, № 3 (2018)
- Страницы: 231-235
- Раздел: Drug Synthesis Methods and Manufacturing Technology
- URL: https://ogarev-online.ru/0091-150X/article/view/245090
- DOI: https://doi.org/10.1007/s11094-018-1796-3
- ID: 245090
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Аннотация
The scientific and technical literature addressing the synthesis of anisotropic iron-oxide nanoparticles of various shapes (cubic, rod-like, clustered, etc.) sized from 10 to 100 nm and their application for diagnostic magnetic resonance imaging (MRI) of tissues and organs is analyzed. The analysis indicates that the nanoparticle shape, size, and surface chemistry affect considerably relaxation parameters T1 and T2. Thus, cubic iron-oxide nanoparticles had the greatest T2 values. Furthermore, rod-like and octapodal nanoparticles also exhibit rather high T2 values so that they can be used as contrast agents for diagnostic MRI.
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A. Nikitin
National University of Science and Technology MISIS (Moscow Institute of Steel and Alloys); Department of Chemistry, M. V. Lomonosov Moscow State University
Автор, ответственный за переписку.
Email: nikitin.chemistry@mail.ru
Россия, 4 Leninskii Prosp., Moscow, 119991; 1/3 Leninskie Gory, GSP-1, Moscow, 119991
M. Khramtsov
National University of Science and Technology MISIS (Moscow Institute of Steel and Alloys)
Email: nikitin.chemistry@mail.ru
Россия, 4 Leninskii Prosp., Moscow, 119991
A. Savchenko
National University of Science and Technology MISIS (Moscow Institute of Steel and Alloys)
Email: nikitin.chemistry@mail.ru
Россия, 4 Leninskii Prosp., Moscow, 119991
M. Abakumov
National University of Science and Technology MISIS (Moscow Institute of Steel and Alloys); N. I. Pirogov Russian National Research Medical University
Email: nikitin.chemistry@mail.ru
Россия, 4 Leninskii Prosp., Moscow, 119991; 1 Ostrovityanova, Moscow, 119997
A. Mazhuga
Department of Chemistry, M. V. Lomonosov Moscow State University; D. I. Mendeleev University of Chemical Technology of Russia
Email: nikitin.chemistry@mail.ru
Россия, 1/3 Leninskie Gory, GSP-1, Moscow, 119991; 9 Miusskaya Sq., Moscow, 125047
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