Enviar artigo por via de e-mail Synthesis and Antiproliferative Activity of New Acylcatechins
- Autores: Pozdeev A.O.1, Rasadkina E.N.1, Burym A.A.1, Knyazev V.V.2, Koroteev M.P.1, Matyushin A.I.2, Koroteev A.M.1, Semeikin A.V.2, Shimanovskii N.L.2
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Afiliações:
- Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
- Medical-Biology Department, Pirogov Russian National Research Medical University
- Edição: Volume 50, Nº 8 (2016)
- Páginas: 523-525
- Seção: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/244428
- DOI: https://doi.org/10.1007/s11094-016-1481-3
- ID: 244428
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Resumo
New peracyl derivatives of the natural flavonoid (±)-catechin were synthesized. It was shown that carboxylic-acid acyl residues enhanced to various degrees the cytotoxicity of peracyl catechins against HeLa cell line. The structures of the synthesized compounds were confirmed by PMR and 13C NMR spectroscopy and elemental analysis. The catechins were compared with previously studied analogous dihydroquercetin derivatives.
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Sobre autores
A. Pozdeev
Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
Autor responsável pela correspondência
Email: Chemdept@mail.ru
Rússia, 3 Nesvizhskii Per., Moscow, 119021
E. Rasadkina
Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
Email: Chemdept@mail.ru
Rússia, 3 Nesvizhskii Per., Moscow, 119021
A. Burym
Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
Email: Chemdept@mail.ru
Rússia, 3 Nesvizhskii Per., Moscow, 119021
V. Knyazev
Medical-Biology Department, Pirogov Russian National Research Medical University
Email: Chemdept@mail.ru
Rússia, 9A/1 Bol’shaya Pirogovskaya St., Moscow, 119435
M. Koroteev
Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
Email: Chemdept@mail.ru
Rússia, 3 Nesvizhskii Per., Moscow, 119021
A. Matyushin
Medical-Biology Department, Pirogov Russian National Research Medical University
Email: Chemdept@mail.ru
Rússia, 9A/1 Bol’shaya Pirogovskaya St., Moscow, 119435
A. Koroteev
Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
Email: Chemdept@mail.ru
Rússia, 3 Nesvizhskii Per., Moscow, 119021
A. Semeikin
Medical-Biology Department, Pirogov Russian National Research Medical University
Email: Chemdept@mail.ru
Rússia, 9A/1 Bol’shaya Pirogovskaya St., Moscow, 119435
N. Shimanovskii
Medical-Biology Department, Pirogov Russian National Research Medical University
Email: Chemdept@mail.ru
Rússia, 9A/1 Bol’shaya Pirogovskaya St., Moscow, 119435
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