电邮这篇文章 Synthesis and Neurotropic Activity of Piperazino-Derivatives of Pyrano[3,4-c]Pyridines
- 作者: Sirakanyan S.N.1, Akopyan É.K.1, Paronikyan R.G.1, Nazaryan I.M.1, Akopyan A.G.1, Ovakimyan A.A.1
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隶属关系:
- A. I. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
- 期: 卷 53, 编号 6 (2019)
- 页面: 495-499
- 栏目: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/245831
- DOI: https://doi.org/10.1007/s11094-019-02026-8
- ID: 245831
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详细
Methods were developed for synthesizing new substituted piperazine derivatives from chloropyrano- [3,4-c]pyridines. Pharmacological screening of the synthesized compounds used the well-known corazole antagonism and open field tests. The rotating rod test was used to evaluate the neurotoxicity of the compounds. The tested compounds displayed neurotropic activity. Several compounds of this series exhibited pronounced anticonvulsant and anxiolytic activity.
作者简介
S. Sirakanyan
A. I. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
编辑信件的主要联系方式.
Email: shnnr@mail.ru
亚美尼亚, 0014, Yerevan, 375014
É. Akopyan
A. I. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: shnnr@mail.ru
亚美尼亚, 0014, Yerevan, 375014
R. Paronikyan
A. I. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: shnnr@mail.ru
亚美尼亚, 0014, Yerevan, 375014
I. Nazaryan
A. I. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: shnnr@mail.ru
亚美尼亚, 0014, Yerevan, 375014
A. Akopyan
A. I. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: shnnr@mail.ru
亚美尼亚, 0014, Yerevan, 375014
A. Ovakimyan
A. I. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: shnnr@mail.ru
亚美尼亚, 0014, Yerevan, 375014
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