Development of the Optimal Diphilic Emulsion Compositions for Phytoextract Suppositories
- Autores: Salova V.G.1, Kozlova Z.M.1, Odintsova E.B.1
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Afiliações:
- I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
- Edição: Volume 52, Nº 12 (2019)
- Páginas: 996-1000
- Seção: Drug Synthesis Methods and Manufacturing Technology
- URL: https://ogarev-online.ru/0091-150X/article/view/245575
- DOI: https://doi.org/10.1007/s11094-019-01940-1
- ID: 245575
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Resumo
Six compositions with various quantities of lipophilic and hydrophilic phases and different emulsifiers were developed. The suppository lipophilic component was type A solid fat; hydrophilic, poly (ethylene glycol) molecules with varying chain lengths and molecular masses. Comprehensive theoretical and experimental results led to formulation of the optimal composition with 35% marigold CO2 extract. The processing parameters for producing such suppositories were optimized.
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Sobre autores
V. Salova
I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: valentina.94.12@gmail.com
Rússia, 8/2 Trubetskaya St., Moscow, 119991
Zh. Kozlova
I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
Email: valentina.94.12@gmail.com
Rússia, 8/2 Trubetskaya St., Moscow, 119991
E. Odintsova
I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
Email: valentina.94.12@gmail.com
Rússia, 8/2 Trubetskaya St., Moscow, 119991
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