Email this article Development of the Optimal Diphilic Emulsion Compositions for Phytoextract Suppositories
- Authors: Salova V.G.1, Kozlova Z.M.1, Odintsova E.B.1
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Affiliations:
- I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
- Issue: Vol 52, No 12 (2019)
- Pages: 996-1000
- Section: Drug Synthesis Methods and Manufacturing Technology
- URL: https://ogarev-online.ru/0091-150X/article/view/245575
- DOI: https://doi.org/10.1007/s11094-019-01940-1
- ID: 245575
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Abstract
Six compositions with various quantities of lipophilic and hydrophilic phases and different emulsifiers were developed. The suppository lipophilic component was type A solid fat; hydrophilic, poly (ethylene glycol) molecules with varying chain lengths and molecular masses. Comprehensive theoretical and experimental results led to formulation of the optimal composition with 35% marigold CO2 extract. The processing parameters for producing such suppositories were optimized.
About the authors
V. G. Salova
I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
Author for correspondence.
Email: valentina.94.12@gmail.com
Russian Federation, 8/2 Trubetskaya St., Moscow, 119991
Zh. M. Kozlova
I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
Email: valentina.94.12@gmail.com
Russian Federation, 8/2 Trubetskaya St., Moscow, 119991
E. B. Odintsova
I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
Email: valentina.94.12@gmail.com
Russian Federation, 8/2 Trubetskaya St., Moscow, 119991
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