Мақаланы E-mail арқылы жіберу Synthesis, Hydrolytic Stability, and Antileukemic Activity of Azacytidine Nucleoside Analogs
- Авторлар: Bozhok T.S.1, Kalinichenko E.N.1, Kuz’mitskii B.B.1, Golubeva M.B.1
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Мекемелер:
- Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus
- Шығарылым: Том 49, № 12 (2016)
- Беттер: 804-809
- Бөлім: Search for New Drugs
- URL: https://ogarev-online.ru/0091-150X/article/view/244296
- DOI: https://doi.org/10.1007/s11094-016-1375-4
- ID: 244296
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
New azacytidine nucleoside analogs with modified carbohydrate moieties were synthesized. Screening identified a highly active 2′-fluoro-containing azacytidine analog that could potentially be of interest as an agent for treating acute myelogenous leukemia and myelodysplastic syndrome.
Авторлар туралы
T. Bozhok
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus
Email: kalinichenko@iboch.bas-net.by
Белоруссия, 5/2 Akad. V. F. Kuprevicha St., Minsk, 220141
E. Kalinichenko
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus
Хат алмасуға жауапты Автор.
Email: kalinichenko@iboch.bas-net.by
Белоруссия, 5/2 Akad. V. F. Kuprevicha St., Minsk, 220141
B. Kuz’mitskii
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus
Email: kalinichenko@iboch.bas-net.by
Белоруссия, 5/2 Akad. V. F. Kuprevicha St., Minsk, 220141
M. Golubeva
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus
Email: kalinichenko@iboch.bas-net.by
Белоруссия, 5/2 Akad. V. F. Kuprevicha St., Minsk, 220141
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