Мақаланы E-mail арқылы жіберу Bioequivalence of a Dosage form of the New Drug Mefebut
- Авторлар: Smirnova L.A.1,2, Suchkov E.A.1,2, Ryabukha A.F.1,2, Kuznetsov K.A.1,2, Velikopol’skaya M.V.1, Tyurenkov I.N.1, Bakulin D.A.1, Stepanova É.F.3, Shevchenko A.M.3
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Мекемелер:
- Volgograd State Medical University
- Volgograd Medical Scientific Center
- Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
- Шығарылым: Том 52, № 6 (2018)
- Беттер: 495-496
- Бөлім: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/245274
- DOI: https://doi.org/10.1007/s11094-018-1846-x
- ID: 245274
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
The bioequivalence of mefebut drug substance and its tablet dosage form was investigated by studying the main pharmacokinetic parameters and calculating the relative bioavailability. The results showed that mefebut circulated for up to 4 h in rabbit blood after peroral administration. The relative bioavailability was 97.4%.
Негізгі сөздер
Авторлар туралы
L. Smirnova
Volgograd State Medical University; Volgograd Medical Scientific Center
Хат алмасуға жауапты Автор.
Email: post@volgmed.ru
Ресей, 1 Pavshikh Bortsov Sq, Volgograd, 400131; 1 Pavshikh Bortsov Sq, Volgograd, 400131
E. Suchkov
Volgograd State Medical University; Volgograd Medical Scientific Center
Email: post@volgmed.ru
Ресей, 1 Pavshikh Bortsov Sq, Volgograd, 400131; 1 Pavshikh Bortsov Sq, Volgograd, 400131
A. Ryabukha
Volgograd State Medical University; Volgograd Medical Scientific Center
Email: post@volgmed.ru
Ресей, 1 Pavshikh Bortsov Sq, Volgograd, 400131; 1 Pavshikh Bortsov Sq, Volgograd, 400131
K. Kuznetsov
Volgograd State Medical University; Volgograd Medical Scientific Center
Email: post@volgmed.ru
Ресей, 1 Pavshikh Bortsov Sq, Volgograd, 400131; 1 Pavshikh Bortsov Sq, Volgograd, 400131
M. Velikopol’skaya
Volgograd State Medical University
Email: post@volgmed.ru
Ресей, 1 Pavshikh Bortsov Sq, Volgograd, 400131
I. Tyurenkov
Volgograd State Medical University
Email: post@volgmed.ru
Ресей, 1 Pavshikh Bortsov Sq, Volgograd, 400131
D. Bakulin
Volgograd State Medical University
Email: post@volgmed.ru
Ресей, 1 Pavshikh Bortsov Sq, Volgograd, 400131
É. Stepanova
Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
Email: post@volgmed.ru
Ресей, 11 Prosp. Kalinina, Pyatigorsk, 357532
A. Shevchenko
Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
Email: post@volgmed.ru
Ресей, 11 Prosp. Kalinina, Pyatigorsk, 357532
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