Optimization of Culture Conditions for the Production of Lovastatin by Aspergillus Terreus in Submerged Fermentation


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Аннотация

The production of lovastatin by Aspergillus terreus PU-PCSIR-1 was studied using submerged fermentation technique. Effects of pH, incubation temperature, incubation time, and the media components on the production of lovastatin were investigated. Maximum lovastatin yield (198.90 mg/L) was achieved after 14 days of incubation at temperature 28°C and pH 7.4. Peptonized milk, linoleic acid, glucose, yeast extract, and trace elements had a positive impact on the production of lovastatin by A. terreus.

Авторлар туралы

M. Azeem

Institute of Industrial Biotechnology, Government College University; Food and Biotechnology Research Centre, Pakistan Council of Scientific and Industrial Research

Email: mmj_bot@yahoo.com
Пәкістан, Lahore; Lahore

Y. Saleem

Food and Biotechnology Research Centre, Pakistan Council of Scientific and Industrial Research

Email: mmj_bot@yahoo.com
Пәкістан, Lahore

Z. Hussain

Institute of Industrial Biotechnology, Government College University

Email: mmj_bot@yahoo.com
Пәкістан, Lahore

S. Zahoor

Department of Biotechnology, Virtual University of Pakistan

Email: mmj_bot@yahoo.com
Пәкістан, Lahore

M. Javed

Institute of Industrial Biotechnology, Government College University

Хат алмасуға жауапты Автор.
Email: mmj_bot@yahoo.com
Пәкістан, Lahore

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