Email this article Validation of a Quantitative Determination Method for Ormustine in a Lyophilized Dosage Form
- Authors: Bunyatyan N.D.1,2, Nikolaeva L.L.1,3, Olefir Y.V.2, Sanarova E.V.3, Oborotova N.A.1,2, Prokof’ev A.B.1,2, Ignat’eva E.V.3, Yartseva I.V.3, Gulyakin I.D.3
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Affiliations:
- I. M. Sechenov First Moscow State Medical University (Sechenov University)
- Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Health of the Russian Federation
- N. N. Blokhin Russian Oncological Research Center, Russian Academy of Medical Sciences
- Issue: Vol 51, No 11 (2018)
- Pages: 1037-1040
- Section: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/244899
- DOI: https://doi.org/10.1007/s11094-018-1735-3
- ID: 244899
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Abstract
Validation results for a spectrophotometric quantitative determination method for ormustine in a lyophilized dosage form are presented. The method is shown to be suitable for quantitative determination of ormustine with respect to parameters such as specificity, linearity, accuracy, repeatability, and intermediate precision.
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About the authors
N. D. Bunyatyan
I. M. Sechenov First Moscow State Medical University (Sechenov University); Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Health of the Russian Federation
Author for correspondence.
Email: ndbun@mail.ru
Russian Federation, Moscow, 119991; Moscow, 127051
L. L. Nikolaeva
I. M. Sechenov First Moscow State Medical University (Sechenov University); N. N. Blokhin Russian Oncological Research Center, Russian Academy of Medical Sciences
Email: ndbun@mail.ru
Russian Federation, Moscow, 119991; Moscow, 115478
Yu. V. Olefir
Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Health of the Russian Federation
Email: ndbun@mail.ru
Russian Federation, Moscow, 127051
E. V. Sanarova
N. N. Blokhin Russian Oncological Research Center, Russian Academy of Medical Sciences
Email: ndbun@mail.ru
Russian Federation, Moscow, 115478
N. A. Oborotova
I. M. Sechenov First Moscow State Medical University (Sechenov University); Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Health of the Russian Federation
Email: ndbun@mail.ru
Russian Federation, Moscow, 119991; Moscow, 127051
A. B. Prokof’ev
I. M. Sechenov First Moscow State Medical University (Sechenov University); Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Health of the Russian Federation
Email: ndbun@mail.ru
Russian Federation, Moscow, 119991; Moscow, 127051
E. V. Ignat’eva
N. N. Blokhin Russian Oncological Research Center, Russian Academy of Medical Sciences
Email: ndbun@mail.ru
Russian Federation, Moscow, 115478
I. V. Yartseva
N. N. Blokhin Russian Oncological Research Center, Russian Academy of Medical Sciences
Email: ndbun@mail.ru
Russian Federation, Moscow, 115478
I. D. Gulyakin
N. N. Blokhin Russian Oncological Research Center, Russian Academy of Medical Sciences
Email: ndbun@mail.ru
Russian Federation, Moscow, 115478
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