Email this article Development of Drug Substances of the Original Class III Antiarrhythmic Drugs Nibentan and Niferidyl
- Authors: Davydova N.K.1
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Affiliations:
- A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences (INEOS RAN)
- Issue: Vol 53, No 9 (2019)
- Pages: 792-796
- Section: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/246012
- DOI: https://doi.org/10.1007/s11094-019-02081-1
- ID: 246012
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Abstract
Publications on the design, synthesis, pharmacological research, and clinical trials of the Russian original class III antiarrhythmic drugs nibentan {(RS)-4-nitro-N-[1-phenyl-5-(diethylamino)pentyl]benzamide hydrochloride} and niferidyl {4-nitro-N-[(1RS)-1-(4-fluorophenyl)-2-(1-ethylpiperidin-4-yl)ethyl]benzamide hydrochloride}are reviewed.
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About the authors
N. K. Davydova
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences (INEOS RAN)
Author for correspondence.
Email: davydova@ineos.ac.ru
Russian Federation, 28 Vavilova St., Moscow, 119991
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