Kinetics of One-Step Mepivacaine Synthesis on Polymers Containing Pd-Nanoparticles

Аннотация

The kinetic factors influencing the hydroacylation of 2,6-dimethylnitrobenzene in the presence of Pd nanoparticles bound to anion exchangers were studied. A general scheme for catalytic synthesis of mepivacaine was proposed based on the obtained kinetic data. The one-step synthesis of mepivacaine was demonstrated to be efficient on various Pd-containing polymer catalysts.