New Herbal Preparation Pancafit and Its Anti-Inflammatory Efficacy

Resumo

A quantitative determination method for total flavonoids recalculated as rutin standard in pancafit dry polyextract obtained from the aerial part of Panzerina lanata (L.) Sojak (Lamiaceae) and leaves of Cacalia hastata L. (Asteraceae) was developed. Intragastric administration of pancafit dry extract at a dose of 100 mg/kg to Wistar rats with acute aseptic inflammation was associated with anti-alterative and anti-exudative activity in addition to accelerated regeneration of damaged tissue. The results indicated that pancafit dry extract should be used as an anti-inflammatory agent in combination with other therapeutic and preventive treatments.