Email this article Hemostasis Parameters and Toxic Effects of 3-Substituted and Condensed Chromen-2-Ones (Coumarins)
- Authors: Ibragimova D.N.1, Fedotova O.V.1, Ozerova A.G.1, Koftin O.V.2, Borodulin V.B.2, Samokhvalov V.A.3
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Affiliations:
- N. G. Chernyshevsky Saratov National Research State University (Saratov State University)
- V. I. Razumovsky Saratov State Medical University, Ministry of Health of the Russian Federation
- University of Alberta
- Issue: Vol 51, No 12 (2018)
- Pages: 1053-1056
- Section: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/244910
- DOI: https://doi.org/10.1007/s11094-018-1739-z
- ID: 244910
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Abstract
Biochemical investigations of 3-substituted chromen-2-ones (coumarins) and those condensed with biologically active azaheterocycles assessed their toxic effects and influence on the blood-coagulation system. The studied group of compounds behaved in the initial time period like the well-known anticoagulant warfarin and exhibited insignificant toxic effects.
About the authors
D. N. Ibragimova
N. G. Chernyshevsky Saratov National Research State University (Saratov State University)
Author for correspondence.
Email: kumargalieva.diana@yandex.ru
Russian Federation, 83 Astrakhanskaya St., Saratov, 410012
O. V. Fedotova
N. G. Chernyshevsky Saratov National Research State University (Saratov State University)
Email: kumargalieva.diana@yandex.ru
Russian Federation, 83 Astrakhanskaya St., Saratov, 410012
A. G. Ozerova
N. G. Chernyshevsky Saratov National Research State University (Saratov State University)
Email: kumargalieva.diana@yandex.ru
Russian Federation, 83 Astrakhanskaya St., Saratov, 410012
O. V. Koftin
V. I. Razumovsky Saratov State Medical University, Ministry of Health of the Russian Federation
Email: kumargalieva.diana@yandex.ru
Russian Federation, 112 Bol’shaya Kazach’ya St., Saratov, 410012
V. B. Borodulin
V. I. Razumovsky Saratov State Medical University, Ministry of Health of the Russian Federation
Email: kumargalieva.diana@yandex.ru
Russian Federation, 112 Bol’shaya Kazach’ya St., Saratov, 410012
V. A. Samokhvalov
University of Alberta
Email: kumargalieva.diana@yandex.ru
Canada, Edmonton
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