Transport Platform Synthesis for Drug Development


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Abstract

Asynthetic scheme for a transport platform for the creation of new diagnostic and therapeutic antitumor drugs that was based on a dendrimer with a core of pentaerythritol tetraglycidyl ether (TGEPE) and dendra with diallylamine was developed. The transport platform was promising for designing targeted antitumor agents for magnetic resonance tomography and nuclear medicine.

About the authors

Yu. V. Stukalov

N. N. Blokhin Russian Cancer Research Center

Email: chem@folium.ru
Russian Federation, 24 Kashirskoe Shosse, Moscow, 115478

E. Yu. Grigor’eva

N. N. Blokhin Russian Cancer Research Center

Email: chem@folium.ru
Russian Federation, 24 Kashirskoe Shosse, Moscow, 115478

V. N. Kulakov

A. I. Burnazyan Federal Medical Biophysics Center, Federal Medico-Biological Agency of Russia

Email: chem@folium.ru
Russian Federation, 46 Zhivopisnaya St, Moscow, 123182

A. Yu. Baryshnikov

N. N. Blokhin Russian Cancer Research Center

Email: chem@folium.ru
Russian Federation, 24 Kashirskoe Shosse, Moscow, 115478

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