Email this article Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide
- Authors: Kholnazarov B.M.1,2, Bunyatyan N.D.3,1, Olefir Y.V.3,1, Bobizoda G.M.2, Prokof’ev A.B.3,1
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Affiliations:
- Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Public Health of the Russian Federation
- Sadriddin Aini Tajik State Pedagogical University
- I. M. Sechenov First Moscow State Medical University
- Issue: Vol 51, No 6 (2017)
- Pages: 453-455
- Section: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/244650
- DOI: https://doi.org/10.1007/s11094-017-1632-1
- ID: 244650
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Abstract
Results from toxicological and pharmacological studies of the iron(II) coordination complex of the immunoactive dipeptide isoleucyltryptophan (timofer) were presented. It was established that timofer was practically nontoxic and exhibited high immunostimulatory activity when combined with viral and bacterial vaccines.
About the authors
B. M. Kholnazarov
Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Public Health of the Russian Federation; Sadriddin Aini Tajik State Pedagogical University
Email: chem@folium.ru
Russian Federation, Moscow, 127051; Dushanbe, 733740
N. D. Bunyatyan
I. M. Sechenov First Moscow State Medical University; Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Public Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, Moscow, 119991; Moscow, 127051
Yu. V. Olefir
I. M. Sechenov First Moscow State Medical University; Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Public Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, Moscow, 119991; Moscow, 127051
G. M. Bobizoda
Sadriddin Aini Tajik State Pedagogical University
Email: chem@folium.ru
Tajikistan, Dushanbe, 733740
A. B. Prokof’ev
I. M. Sechenov First Moscow State Medical University; Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Public Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, Moscow, 119991; Moscow, 127051
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