The Main Structural Types of Inhibitors of Matrix Metalloproteinases
- Авторы: Kapranov L.E.1, Reznikov A.N.1, Klimochkin Y.N.1
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Учреждения:
- Samara State Technical University
- Выпуск: Том 51, № 3 (2017)
- Страницы: 175-181
- Раздел: Search for New Drugs
- URL: https://ogarev-online.ru/0091-150X/article/view/244524
- DOI: https://doi.org/10.1007/s11094-017-1577-4
- ID: 244524
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Аннотация
This review addresses the main structural types of matrix metalloproteinase (MMP) inhibitors - hydroxamic acid derivatives, sulfonamides, bisphosphonates, compounds combining phosphoryl and hydroxamate groups, and functional derivatives of phosphonic and phosphinic acids. The selectivity of the inhibitory actions of these substances in relation to different types of MMP and the potential for the practical application of these substances in cancer treatment are discussed.
Об авторах
L. Kapranov
Samara State Technical University
Email: orgphosphorus@yandex.ru
Россия, 244 Molodogvardeiskaya Street, Samara, 443100
A. Reznikov
Samara State Technical University
Автор, ответственный за переписку.
Email: orgphosphorus@yandex.ru
Россия, 244 Molodogvardeiskaya Street, Samara, 443100
Yu. Klimochkin
Samara State Technical University
Email: orgphosphorus@yandex.ru
Россия, 244 Molodogvardeiskaya Street, Samara, 443100
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