Email this article Pharmacokinetics of the Polyaldehyde Dextran Conjugate with Isonicotinic Acid Hydrazide
- Authors: Starostenko A.A.1, Medvedev V.S.1, Troitskii A.V.1, Bystrova T.N.1, Arkhipov S.A.1, Shkurupii V.A.1
-
Affiliations:
- Research Institute of Experimental and Clinical Medicine, Siberian Branch, Russian Academy of Medical Sciences
- Issue: Vol 50, No 9 (2016)
- Pages: 577-579
- Section: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/244440
- DOI: https://doi.org/10.1007/s11094-016-1493-z
- ID: 244440
Cite item
Open Access
Access granted
Subscription Access
Abstract
The pharmacokinetics of the promising antituberculosis drug dextrazide, the conjugate of polyaldehyde dextran with isonicotinic acid hydrazide, were studied using outbred ICR mice. The obtained results were indicative of two-phase dextrazide pharmacokinetics.
Keywords
About the authors
A. A. Starostenko
Research Institute of Experimental and Clinical Medicine, Siberian Branch, Russian Academy of Medical Sciences
Email: chem@folium.ru
Russian Federation, Novosibirsk, 630117
V. S. Medvedev
Research Institute of Experimental and Clinical Medicine, Siberian Branch, Russian Academy of Medical Sciences
Email: chem@folium.ru
Russian Federation, Novosibirsk, 630117
A. V. Troitskii
Research Institute of Experimental and Clinical Medicine, Siberian Branch, Russian Academy of Medical Sciences
Email: chem@folium.ru
Russian Federation, Novosibirsk, 630117
T. N. Bystrova
Research Institute of Experimental and Clinical Medicine, Siberian Branch, Russian Academy of Medical Sciences
Email: chem@folium.ru
Russian Federation, Novosibirsk, 630117
S. A. Arkhipov
Research Institute of Experimental and Clinical Medicine, Siberian Branch, Russian Academy of Medical Sciences
Email: chem@folium.ru
Russian Federation, Novosibirsk, 630117
V. A. Shkurupii
Research Institute of Experimental and Clinical Medicine, Siberian Branch, Russian Academy of Medical Sciences
Email: chem@folium.ru
Russian Federation, Novosibirsk, 630117
Supplementary files
