Mechanisms of Antiradical Activity of 2,3,5,6,8-Pentahydroxy-7-Ethyl-1,4-Naphthoquinone (A Review)
- Авторы: Talalaeva O.S.1, Zverev Y.F.1, Bryukhanov V.M.1
- 
							Учреждения: 
							- Altai State Medical University, Ministry of Health of the Russian Federation
 
- Выпуск: Том 50, № 6 (2016)
- Страницы: 353-357
- Раздел: Molecular-Biological Problems of Drug Design and Mechanism of Drug Action
- URL: https://ogarev-online.ru/0091-150X/article/view/244393
- DOI: https://doi.org/10.1007/s11094-016-1450-x
- ID: 244393
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Аннотация
The role of the antioxidant properties of 2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone in the manifestation of its pharmacological effects is reviewed. Issues with pleiotropic cellular-molecular mechanisms of echinochrome A action are considered with emphasis on the unique antioxidant activity of 2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone. These properties in combination with a low destructive potential account for the prospects of expanding the therapeutic use of echinochrome A.
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O. Talalaeva
Altai State Medical University, Ministry of Health of the Russian Federation
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Barnaul, Altai Krai, 656038						
Ya. Zverev
Altai State Medical University, Ministry of Health of the Russian Federation
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Barnaul, Altai Krai, 656038						
V. Bryukhanov
Altai State Medical University, Ministry of Health of the Russian Federation
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Barnaul, Altai Krai, 656038						
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