Experimental Study of the Biocompatibility of Soft Tissues and a Finely Dispersed Sorbent Containing Silver
- 作者: Popova T.V.1, Tolstikova T.G.2, Letyagin A.Y.1, Rachkovskaya L.N.1, Burmistrov V.A.1
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隶属关系:
- Institute of Clinical and Experimental Lymphology
- N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences
- 期: 卷 50, 编号 3 (2016)
- 页面: 152-155
- 栏目: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/244334
- DOI: https://doi.org/10.1007/s11094-016-1413-2
- ID: 244334
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详细
The physicochemical and biological properties of a new finely dispersed Si- and Al-containing sorbent are presented. Its modification using silver nanoclusters immobilized on the sorbent-particle surface is described. The parameters of the sorbent porous structure, its sorption activity, and the rate of silver release from the sorbent surface in contact with a liquid medium are determined. Both the sorbent matrix and the original silver-modified sorbent are well tolerated by experimental animals upon intramuscular administration and cause no changes in the behavior, weight, and appearance of the animals. Results from studies of the leukocyte, platelet, and red-blood-cell pools of peripheral blood also confirm that the sorbents are biocompatible with body tissues.
作者简介
T. Popova
Institute of Clinical and Experimental Lymphology
编辑信件的主要联系方式.
Email: argentum.popova@mail.ru
俄罗斯联邦, Novosibirsk, 630117
T. Tolstikova
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: tg_tolstikova@mail.ru
俄罗斯联邦, Novosibirsk, 630090
A. Letyagin
Institute of Clinical and Experimental Lymphology
Email: tg_tolstikova@mail.ru
俄罗斯联邦, Novosibirsk, 630117
L. Rachkovskaya
Institute of Clinical and Experimental Lymphology
Email: tg_tolstikova@mail.ru
俄罗斯联邦, Novosibirsk, 630117
V. Burmistrov
Institute of Clinical and Experimental Lymphology
Email: tg_tolstikova@mail.ru
俄罗斯联邦, Novosibirsk, 630117
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