Effect of Total Flavonoids from Vexibia alopecuroides on the Course of Experimental Diabetes in Rats


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Abstract

Total flavonoids from Vexibia alopecuroides administered for two weeks to rats with alloxan diabetes lowered the blood glucose level and increased the lactic-pyruvic acid redox potential and liver glycogen level. Lipid metabolism, the antioxidant protection system, and peroxidation processes showed a distinct tendency to normalize in vivo through the influence of the total flavonoids. In this respect, total flavonoids from V. alopecuroides were as effective in the conducted experiments as the known anti-diabetes agent diabeton.

About the authors

N. Kh. Yuldasheva

S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan

Email: chem@folium.ru
Uzbekistan, Tashkent

F. R. Égamova

S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan

Email: chem@folium.ru
Uzbekistan, Tashkent

G. I. Ismailova

S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan

Email: chem@folium.ru
Uzbekistan, Tashkent

Z. A. Khushbaktova

S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan

Email: chem@folium.ru
Uzbekistan, Tashkent

S. M. Yusupova

S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan

Email: chem@folium.ru
Uzbekistan, Tashkent

V. N. Syrov

S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan

Email: chem@folium.ru
Uzbekistan, Tashkent

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