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Reaction of 5,5-Dihalogen-6-hydroxy-6-methyldihydropyrimidine-2,4-diones with KI in a Water–Acetone Medium
- Authors: Chernikova I.B.1, Yunusov M.S.1
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Affiliations:
- Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences
- Issue: Vol 95, No 11-12 (2025)
- Pages: 505-510
- Section: Articles
- URL: https://ogarev-online.ru/0044-460X/article/view/362174
- DOI: https://doi.org/10.7868/S3034559625110034
- ID: 362174
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Abstract
Treatment of 5,5-dichloro-6-hydroxy-6-methyluracil with an excess of KI in an aqueous acetone medium yielded 5-hydroxy-6-methyluracil. A similar reaction of 5-bromo-5-chloro- and 5,5-dibromo-6-hydroxy derivatives of 6-methyluracil, as well as 5,5-dibromo-6-hydroxy-5,6-dihydrouracil, leads to the formation of 5-monohalogen derivatives via a halophilic mechanism.
Keywords
About the authors
I. B. Chernikova
Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences
Email: inna.b.chernikova@yandex.ru
ORCID iD: 0000-0002-1713-855X
Ufa, Russia
M. S. Yunusov
Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences
Email: inna.b.chernikova@yandex.ru
ORCID iD: 0009-0006-1608-5784
Ufa, Russia
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