The effectiveness of using a combination of laser radiation with wavelengths of 585 and 1064 nm in the treatment of patients with basal cell skin cancer
- Authors: Saytburkhanov R.R.1, Plakhova X.I.1, Kondrakhina I.N.1, Kubanov А.A.1
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Affiliations:
- State Research Center of Dermatovenereology and Cosmetology
- Issue: Vol 99, No 6 (2023)
- Pages: 37-44
- Section: ORIGINAL STUDIES
- URL: https://ogarev-online.ru/0042-4609/article/view/252155
- DOI: https://doi.org/10.25208/vdv16047
- ID: 252155
Cite item
Abstract
Background. Basal cell skin cancer is the most common skin malignancy, and its incidence has been rapidly increasing throughout the world in recent decades.
Aims. To study the effectiveness of using laser radiation with a wavelength of 585 nm and 1064 nm in a sequential (sequential) combined mode for the treatment of patients with superficial and nodular forms of basal cell skin cancer using dermoscopic and confocal microscopic in vivo examination.
Materials and methods. The study included 30 patients with histologically confirmed basal cell skin cancer, who received treatment in the conditions of the Consultative and Diagnostic Center of the State Research Center of Dermatovenereology and Cosmetology of Russian Ministry of Health in the period from 2020 to 2021, using a pulsed dye laser (wavelength 585 nm) and long-pulse neodymium laser (wavelength 1064 nm).
Results. In the subgroup of patients with the nodular form of basal cell carcinoma (n = 15): in 11 patients the duration of treatment was 1 procedure, in 3 patients – 2 procedures, in 1 patient — 3 procedures. In the subgroup of patients with superficial basal cell carcinoma (n = 15 ): in 2 patients the course of treatment was 2 procedures, in 13 patients — 1 procedure. Patients have now completed treatment and are being followed up with visits every 6 months for 3 years. According to dermoscopic and confocal microscopic studies, there is no evidence of continued growth and relapse in all patients. No side effects or adverse events were recorded.
Conclusions. The combined sequential use of 585 nm and 1064 nm laser radiation may be an effective treatment for patients with low-risk basal cell skin cancer of recurrence. The results of our study indicate that clinical tumor removal without scarring can be achieved and may be an alternative treatment option for those who do not wish to use traditional surgical approaches.
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##article.viewOnOriginalSite##About the authors
Rifat R. Saytburkhanov
State Research Center of Dermatovenereology and Cosmetology
Author for correspondence.
Email: rifat03@yandex.ru
ORCID iD: 0000-0001-6132-5632
SPIN-code: 1149-2097
dermatovenereologist
Russian Federation, 3 bldg 6 Korolenko street, 107076 MoscowXenia I. Plakhova
State Research Center of Dermatovenereology and Cosmetology
Email: plahova@cnikvi.ru
ORCID iD: 0000-0003-4169-4128
SPIN-code: 7634-5521
MD, Dr. Sci. (Med.)
Russian Federation, 3 bldg 6 Korolenko street, 107076 MoscowIrina N. Kondrakhina
State Research Center of Dermatovenereology and Cosmetology
Email: kondrakhina77@gmail.com
ORCID iD: 0000-0003-3662-9954
SPIN-code: 8721-9424
MD, Dr. Sci. (Med.)
Russian Federation, 3 bldg 6 Korolenko street, 107076 MoscowАlexey A. Kubanov
State Research Center of Dermatovenereology and Cosmetology
Email: alex@cnikvi.ru
ORCID iD: 0000-0002-7625-0503
SPIN-code: 8771-4990
MD, Dr. Sci. (Med.), Professor, Academician of the Russian Academy of Sciences
Russian Federation, 3 bldg 6 Korolenko street, 107076 MoscowReferences
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