Experience of using ustekinumab in the treatment of a patient with HIV-associated psoriasis and anogenital warts

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Abstract

The article presents an analysis of the literature of patients with HIV infection suffering from psoriasis. The clinical picture, laboratory data, and treatment of a patient suffering from psoriasis, psoriatic arthritis, anogenital venereal warts associated with HIV infection are described. Against the background of the use of an IL 12.23 inhibitor, regression of anogenital warts, resolution of psoriatic rashes, and relief of articular syndrome were noted.

About the authors

M. I. Babkova

Regional dermatovenerologic dispensary

Email: mariababkova@gmail.com
ORCID iD: 0000-0002-4906-4297
SPIN-code: 7896-2629
Russian Federation, Khabarovsk

M. I. Arshinsky

Regional dermatovenerologic dispensary

Email: kkvd80@inbox.ru
ORCID iD: 0000-0003-2952-9082
Russian Federation, Khabarovsk

Z. V. Frolova

Regional dermatovenerologic dispensary

Email: frolowazoya@yandex.ru
ORCID iD: 0000-0002-2633-1452
Russian Federation, Khabarovsk

O. A. Chudina

Regional dermatovenerologic dispensary

Email: olya_chudina@mail.ru
ORCID iD: 0000-0003-0149-1115
Russian Federation, Khabarovsk

J. S. Mitrofanova

Regional dermatovenerologic dispensary

Email: kkvd80@inbox.ru
ORCID iD: 0000-0001-7657-0833
Russian Federation, Khabarovsk

S. K. Batalova

Regional dermatovenerologic dispensary

Author for correspondence.
Email: kkvdv@mail.ru
ORCID iD: 0000-0002-9598-3120
Russian Federation, Khabarovsk

References

  1. Menon K, Van Voorhees AS, Bebo BF Jr, Gladman DD, Hsu S, Kalb RE, et al. Psoriasis in patients with HIV infection: from the medical board of the National Psoriasis Foundation. J Am Acad Dermatol. 2010;62(2):291–299. doi: 10.1016/j.jaad.2009.03.047
  2. de Camargo CC, Tasca KI, Mendes MB, Miot HA, de Souza Ldo R. Prevalence of Anogenital Warts in Men with HIV/AIDS and Associated Factors. Open AIDS J. 2014;8:25–30. doi: 10.2174/1874613601408010025
  3. Wang DM, Fernandez AP, Calabrese CM, Calabrese LH. Treatment of psoriasis with ustekinumab in a patient with HIV-related Kaposi sarcoma. Clin Exp Dermatol. 2019;44(1):113–115. doi: 10.1111/ced.13630
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  5. Paparizos V, Rallis E, Kirsten L, Kyriakis K. Ustekinumab for the treatment of HIV psoriasis. J Dermatolog Treat. 2012;23(6):398–399. doi: 10.3109/09546634.2011.579085
  6. Saeki H, Ito T, Hayashi M, Fukuchi O, Umezawa Y, Nobeyama Y, Teruya K, et al. Successful treatment of ustekinumab in a severe psoriasis patient with human immunodeficiency virus infection. J Eur Acad Dermatol Venereol. 2015;29(8):1653–1655. doi: 10.1111/jdv.12531
  7. Bardazzi F, Magnano M, Campanati A, Loconsole F, Carpentieri A, Potenza C, et al. Biologic Therapies in HIV-infected Patients with Psoriasis: An Italian Experience. Acta Derm Venereol. 2017;97(8):989–990. doi: 10.2340/00015555-2698
  8. Montazeri A, Kanitakis J, Bazex J. Psoriasis and HIV infection. Int J Dermatol. 1996;35(7):475–479. doi: 10.1111/j.1365-4362.1996.tb01658.x
  9. Menon K, Van Voorhees AS, Bebo BF Jr, Gladman DD, Hsu S, Kalb RE, et al; National Psoriasis Foundation. Psoriasis in patients with HIV infection: from the medical board of the National Psoriasis Foundation. J Am Acad Dermatol. 2010;62(2):291–299. doi: 10.1016/j.jaad.2009.03.047
  10. Boehncke WH, Schön MP. Psoriasis. Lancet. 2015;386(9997):983–994. doi: 10.1016/S0140-6736(14)61909-7

Supplementary files

Supplementary Files
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1. JATS XML
2. Figure. (a, c, e, g, i) patient in October 2018, before starting therapy, (b, d, h, j) patient in January 2019, 16 weeks of ustekinumab therapy, (f) patient in June 2020, 88 weeks of ustekinumab therapy

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Copyright (c) 2021 Babkova M.I., Arshinsky M.I., Frolova Z.V., Chudina O.A., Mitrofanova J.S., Batalova S.K.

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