Functional condition of the lip skin: effect of the age and hormone replacementtherapy
- Authors: Gubanova EI1, Gubanova Y.I1
-
Affiliations:
- Центр косметологической коррекции«Эклан», Клиника превентивной медицины «Валлекс М»
- Issue: Vol 86, No 3 (2010)
- Pages: 94-99
- Section: Articles
- URL: https://ogarev-online.ru/0042-4609/article/view/117273
- DOI: https://doi.org/10.25208/vdv874
- ID: 117273
Cite item
Full Text
Abstract
Goal: To assess the effect of the age and hormone replacement therapy (HRT) on the functional properties of the lip skin in women.
Materials and methods: The author conducted a comparative study of the functional properties of lips in 4 groups (young women
at the age of 20-34 and 40-49 with regular menstrual cycles, two groups of post-menopausal women taking and not taking HRT).
The following was assessed: degree of skin oiliness on the forehead, on the lower lip - transepidermal waster loss (TEWL), mechanical
deformation and elasticity, color, tactile sensitivity, hydration.
Results: Changes in the TEWL, mechanical deformation and tactile sensitivity are age-related while a more saturated color of the lips may be caused by HRT. Skin oiliness is also related to the hormonal profile in women. No effect of the age or hormonal status
on the moisture content in the lips was revealed. The study confirmed that the upper lip has a greater moisture content than the lower one.
Conclusion: The study revealed a hormonal effect on the skin fat secretion, which reduces during the post-menopausal period and is stimulated by hormone replacement therapy. Age-related changes in the elasticity and tactile sensitivity of the vermilion border
are similar to those in skin parameters.
Materials and methods: The author conducted a comparative study of the functional properties of lips in 4 groups (young women
at the age of 20-34 and 40-49 with regular menstrual cycles, two groups of post-menopausal women taking and not taking HRT).
The following was assessed: degree of skin oiliness on the forehead, on the lower lip - transepidermal waster loss (TEWL), mechanical
deformation and elasticity, color, tactile sensitivity, hydration.
Results: Changes in the TEWL, mechanical deformation and tactile sensitivity are age-related while a more saturated color of the lips may be caused by HRT. Skin oiliness is also related to the hormonal profile in women. No effect of the age or hormonal status
on the moisture content in the lips was revealed. The study confirmed that the upper lip has a greater moisture content than the lower one.
Conclusion: The study revealed a hormonal effect on the skin fat secretion, which reduces during the post-menopausal period and is stimulated by hormone replacement therapy. Age-related changes in the elasticity and tactile sensitivity of the vermilion border
are similar to those in skin parameters.
About the authors
E I Gubanova
Центр косметологической коррекции«Эклан», Клиника превентивной медицины «Валлекс М»
Email: Elena_gubanova@mail.ru
дерматовенеролог, косметолог, главный врачк.м.н; Центр косметологической коррекции«Эклан», Клиника превентивной медицины «Валлекс М»
Ye I Gubanova
References
- Nagase KI, Ando Y, Hirose O, Okada T, Tamaoki I, Hanada K, Konishi
- H. Characters and age-associated changes on lip surface. Nihon Keshohin Gijutsushakaishi 1991; 25: 21-26.
- Leveque JL, Gubanova E. Influence of age on the lips and perioral skin. Dermatology 2004; 208: 307-313.
- Nazzaro-Porro M, Passi S, Boniforti L, Belsito F. Effects of aging on fatty acids in skin surface lipids. J Invest Dermatol 1979; 73: 112-117.
- Sator PG, Schmidt JB, Sator MO, Huber JC, Honigsman H. The influence of hormone replacement therapy on skin ageing: a pilot study. Maturitas 2001; 39: 43-55.
- Leveque JL, Querleux B. SkinChip, a new tool for investigating the skin surface in vivo. Skin Res Technol 2003; 9: 343-347.
- Woodward KL. The relationship between skin compliance, age, gender, and tactile discriminative thresholds in humans. Somatosens Mot Res. 1993. 10 (1): Р. 63-70.
- Stevens JC, Patterson MQ. Dimensions of spatial acuity in the touch sense: changes over the life span. Somatosens Mot Res. 1995. 12 (1): Р. 29-47. 8. Besné I, Descombes C, Breton L. Effect of age and anatomical site on density of sensory innervation in human epidermis. Arch Dermatol. 2002 Nov: 138 (11): Р. 1445-50.
- Escoffier C, de Rigal J, Rochefort A, Vasselet R, Leveˆque JL, Agache P. Age-related mechanical properties of human skin: an in vivo study. J Invest Dermatol 1989; 93: 353-357.
- Pierard-Franchimont C, Cornil F, Dehavay J, Deleixhe-Mauvin F, Letot B, Pierard GE. Climacteric skin aging of the face, a prospective longitudinal comparative trial on the effect of oral hormone replacement therapy. Maturitas 1999; 32: 87-93.
- Leveque JL, Dresler J, Ribot-Ciscar E, Roll JP, Poelman Ch. Changes in the tactile spatial discrimination and cutaneous coding properties by skin hydration in the elderly. J Invest Dermatol 2000; 115: 454-458.
- Bolton CF, Winkelmann RK. A quantitative study of Meissner's corpuscules in man. Neurology 1965; 16: 1-9.
Supplementary files
