Hyperpigmentation problem and a new method for solving it
- Authors: ANDREYEVA Y.V1, OLISOVA OY.1
-
Affiliations:
- I.M. Sechenov First Moscow State Medical University
- Issue: Vol 89, No 6 (2013)
- Pages: 80-84
- Section: Articles
- URL: https://ogarev-online.ru/0042-4609/article/view/117103
- DOI: https://doi.org/10.25208/vdv614
- ID: 117103
Cite item
Full Text
Abstract
Goal. To assess the efficacy and safety of Neoton serum and cream for the treatment of chloasma. Materials and methods. Ten women aged 25—60 suffering from chloasma received Neoton (Neoton cream in the morning and Neoton serum in the evening) for a month. The level of melanin in lesion foci was determined prior to and after the treatment using the Multi Skin Test Center MC 750 (Germany). Results. Prior to the treatment, the level of melanin ranged from 89 to 124 (for normal skin: from 6 to 40). The treatment with Neoton drugs resulted in a complete regression of eruptions in 30% of the women, substantial improvement in 60% of the patients and improvement in 10% of them. A reduction in the level of melanin ranging from 15 to 68 serves as an objective proof of the drug efficacy. Neither of the patients developed any adverse effects. Conclusion. Good tolerance and efficacy of Neoton serum and cream for the treatment of hyperpigmentation (chloasma) were demonstrated.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
YE V ANDREYEVA
I.M. Sechenov First Moscow State Medical Universityврач лечебно-диагностического отделения клиники кожных и венерических болезней им. В.А. Рахманова УКБ № 2
O YU OLISOVA
I.M. Sechenov First Moscow State Medical University
Email: olisovaolga@mail.ru
д.м.н., профессор, заведующий кафедрой кожных и венерических болезней лечебного факультета
References
- Бабаянц Р.С., Лоншаков Ю.И. Расстройства пигментации кожи. М: Медицина 1978; 144
- Мордовцева В.Н., Цветкова Г.М. Патология кожи. В 2 т. Т.1. Общая патология кожи. М: Медицина 1993
- Нетруненко И.Ю., Игнатьев Д.В. Гиперпигментация: проблемы и пути их решения. Consilium medicum. Дерматология 2007; 2: 12—16
- Prota G., Napolitano A. Melanin pigmentation and skin photoprotection — recent advances and opportunites. Cosmetic Science Conference (Montjuic-2, Barcelona): Proceedings, 2000; 5—11
- Олисова О.Ю. Новые возможности в лечении гиперпигментаций. Лечащий врач 2011; 5: 39—40
- Вулф К., Джонсон Р., Сюрмонд Д. Дерматология по Томасу Фицпатрику. М: Практика, 2007; 1248
- Ахтямов С.Н., Бутов Ю.С. Практическая дерматокосметология. М: Медицина 2003
- Халдина М.В., Черкасова М.В. Гиперпигментация в практике косметолога. Клин дерматол венерол 2005; 4: 107—114
- Akiu S., Suzuki Y., Asahara T. et al. Inhibitory effect of arbutin on melanogenesis — biochemical study using cultured B16 melanoma cells. Nippon Hifuca Akkai Zacchi 1991; 101 (6): 609—613.
- Wester R.C., Melendres J., Hui X. et al. Human in vivo and in vitro hydroquinone bioavailability, metabolism and disposition. J Toxicol Environ Health 1998; 54 (4): 301—317.
Supplementary files
