Current approaches to the treatment of vulvovaginitis caused by opportunistic microorganisms taking into consideration the antibacterial resistance of infectious agents
- 作者: Rakhmatulina MR1
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隶属关系:
- State Research Center of Dermatovenereology and Cosmetology, Ministry of Health Care of the Russian Federation
- 期: 卷 89, 编号 2 (2013)
- 页面: 44-52
- 栏目: Articles
- URL: https://ogarev-online.ru/0042-4609/article/view/117048
- DOI: https://doi.org/10.25208/vdv565
- ID: 117048
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Goal of the study. To study the qualitative and quantitative composition of the vaginal microcenosis in women of childbearing potential with vulvovaginitis and determine the sensitivity indices of opportunistic microorganisms being etiological agents of vulvovaginitis concerning antibacterial drugs. Materials and methods. Samples of the vaginal fluid obtained from 264 women (198 patients with clinical and laboratory signs of vulvovaginitis and 66 clinically healthy women) as well as 190 isolates of opportunistic microbial agents were analyzed with the use of microscopic and cultural methods as well as polymerase chain reaction. Results. The authors determined the composition of the vaginal microbiocenosis in women suffering from vulvovaginitis characterized by the prevalence of Corynebacterium spp., E. coli, E. faecalis, S. saprophiticus, K. pneumoniae, S. anginosus, S. agalactiae in the amount exceeding 10 2—10 4 CFU/ml and in associations of four or more microorganisms. The authors revealed that opportunistic microorganisms had the highest sensitivity to amoxicillin/clavulanic acid, nitrofuran and ceftriaxone.
作者简介
M Rakhmatulina
State Research Center of Dermatovenereology and Cosmetology, Ministry of Health Care of the Russian Federation
Email: rahmatulina@cnikvi.ru
д.м.н., ведущий научный сотрудник, и. о. заведующего отделом инфекций, передаваемых половым путем Korolenko str. 3, bldg 6, 107076, Moscow, Russia
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