Pathomorphological and clinical characteristics of blastic plasmocytoid dendritic cell neoplasm. Case report

封面

如何引用文章

全文:

详细

The paper reveals the 5 cases date about blastic plasmacytoid dendritic cell neoplasm. The presented information demonstrates morphological, immunohistochemical data and clinical manifestations.

作者简介

Andrei Sherstnev

National Research Center for Hematology

编辑信件的主要联系方式.
Email: sherstnevandrejj@mail.ru
ORCID iD: 0000-0002-1597-4591

аспирант патологоанатомического отд-ния, врач-стажер

俄罗斯联邦, Moscow

Alla Kovrigina

National Research Center for Hematology

Email: sherstnevandrejj@mail.ru
ORCID iD: 0000-0002-1082-8659

д-р биол. наук, зав. патологоанатомическим отд-нием

俄罗斯联邦, Moscow

Tatiana Solovyova

National Research Center for Hematology

Email: sherstnevandrejj@mail.ru
ORCID iD: 0000-0001-8246-6581

канд. мед. наук, врач-гематолог

俄罗斯联邦, Moscow

Tatiana Moiseeva

National Research Center for Hematology

Email: sherstnevandrejj@mail.ru
ORCID iD: 0000-0001-9591-8508

канд. мед. наук, врач-гематолог, зав. отд-нием химиотерапии гематологических заболеваний с дневным стационаром

俄罗斯联邦, Moscow

参考

  1. Swerdlow SH, Campo E, Harris NL, et al. WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues (Revised 4th edition). IARC: Lyon, 2017; p. 173-8.
  2. Bueno C, Almeida J, Lucio P, et al. Incidence and characteristics of CD4(+)/HLA DRhi dendritic cell malignancies. Haematologica. 2004;89(1):58-69.
  3. Wang H, Cao J, Hong X. Blastic plasmacytoid dendritic cell neoplasm without cutaneous lesion at presentation: case report and literature review. Acta Haematologica. 2012;127(2):124-7. doi: 10.1159/000334703
  4. Trottier AM, Cerquozzi S, Owen CJ. Blastic plasmacytoid dendritic cell neoplasm: challenges and future prospects. Blood Lymphat Cancer. 2017;7:85-93. doi: 10.2147/BLCTT.S132060
  5. Adachi M, Maeda K, Takekawa M, et al. High expression of CD56 (N-CAM) in a patient with cutaneous CD4-positive lymphoma. Am J Hematol. 1994;47(4):278-82. doi: 10.1002/ajh.2830470406
  6. Kazakov DV, Mentze T, Burg G, et al. Blastic natural killer-cell lymphoma of the skin associated with myelodysplastic syndrome or myelogenous leukaemia: a coincidence or more? Br J Dermatol. 2003;149:869-76. doi: 10.1046/j.1365-2133.2003.05639.x
  7. Dzionek A, Inagaki Y, Okawa K, et al. Plasmacytoid dendritic cells: from specific surface markers to specific cellular functions. Hum Immunol. 2002;63(12):1133-48. doi: 10.1016/s0198-8859(02)00752-8
  8. Saadeh D, Kurban M, Abbas O. Plasmacytoid dendritic cell role in cutaneous malignancies. J Dermatol Sci. 2016;83(1):3-9. doi: 10.1016/j.jdermsci.2016.05.008
  9. Jegalian AG, Buxbaum NP, Facchetti F, et al. Blastic plasmacytoid dendritic cell neoplasm in children: diagnostic features and clinical implications. Haematologica. 2010;95(11):1873-9. doi: 10.3324/haematol.2010.026179
  10. Nomburg J, Bullman S, Chung SS, et al. Comprehensive metagenomic analysis of blastic plasmacytoid dendritic cell neoplasm. Blood Adv. 2020;4(6):1006-11. doi: 10.1182/bloodadvances.2019001260
  11. Testa U, Pelosi E, Frankel A. CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies. Biomark Res. 2014;2(1):4. doi: 10.1186/2050-7771-2-4
  12. Bôle-Richard E, Fredon M, Biichlé S, et al. CD28/4-1BB CD123 CAR T cells in blastic plasmacytoid dendritic cell neoplasm. Leukemia. 2020;34(12):3228-41. doi: 10.1038/s41375-020-0777-1
  13. Torres ANB, Cats D, Mei H, et al. Whole-genome analysis uncovers recurrent IKZF1 inactivation and aberrant cell adhesion in blastic plasmacytoid dendritic cell neoplasm. Genes Chromosomes Cancer. 2020;59(5):295-308. doi: 10.1002/gcc.22831
  14. Ceribelli M, Hou ZE, Kelly PN, et al. A druggable TCF4- and BRD4-dependent transcriptional network sustains malignancy in blastic plasmacytoid dendritic cell neoplasm. Cancer Cell. 2016;30(5):764-78. doi: 10.1016/j.ccell.2016.10.002
  15. Sukswai N, Aung PP, Yin CC, et al. Dual expression of TCF4 and CD123 is highly sensitive and specific for blastic plasmacytoid dendritic cell neoplasm. Am J Surg Pathol. 2019;43(10):1429-37. doi: 10.1097/PAS.0000000000001316
  16. Agha M, Monaghan S, Swerdlow S. Venetoclax in a Patient with a Blastic Plasmacytoid Dendritic-Cell Neoplasm. New England J Med. 2018;379(15):1479-81. doi: 10.1056/NEJMc1808354
  17. Aung P, Sukswai N, Nejati R, et al. PD1/PD-L1 Expression in Blastic Plasmacytoid Dendritic Cell Neoplasm. Cancers. 2019;11:695. doi: 10.3390/cancers11050695

补充文件

附件文件
动作
1. JATS XML
2. Fig. 1. Observation 1. Lymph node biopsy. Blast tumor of plasmacytoid dendritic cells.

下载 (573KB)
3. Fig. 2. Observation 2. Skin lesion in a blast tumor from plasmacytoid dendritic cells.

下载 (563KB)

版权所有 © Consilium Medicum, 2022

Creative Commons License
此作品已接受知识共享署名-非商业性使用-相同方式共享 4.0国际许可协议的许可。
 
 


Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).